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  1. Systemic sclerosis (SSc) is a chronic disease characterized by autoimmunity, vasculopathy, and visceral and cutaneous fibrosis. Vitamin D has several functions in the immunological system, and different studie...

    Authors: Laiana Schneider, Vanessa Hax, Odirlei Monticielo, Tamires Ferri Macedo, Roberta Kern Menna Barreto, Natália Aydos Marcondes and Rafael Chakr
    Citation: Advances in Rheumatology 2021 61:34
  2. Vasculitis damage index (VDI) is a validated damage index for systemic vasculitis, and as Behçet’s disease is considered one of systemic vascular disease we aimed to study the relationship of the vasculitis da...

    Authors: Fatema T. Elgengehy, Sherif M. Gamal, Nesreen Sobhy, Ibrahem Siam, Ahmed M. Soliman, Ghada W. Elhady and Tamer A. Gheita
    Citation: Advances in Rheumatology 2021 61:33
  3. To evaluate the perception of rheumatologists regarding the recommendations of the Brazilian Consensus for detection of Autoantibodies (BCA) on HEp-2 Cells by Indirect Immunofluorescence assay (IFA) and how BC...

    Authors: Isadora Carvalho Medeiros Francescantonio, Leandro Augusto Rodrigues dos Santos, Paulo Luiz Carvalho Francescantonio, Luiz Eduardo Coelho Andrade and Wilson de Melo Cruvinel
    Citation: Advances in Rheumatology 2021 61:32
  4. Osteoarthritis (OA) is defined as a degenerative disease. Pivotal roles of long non-coding RNA (lncRNAs) in OA are widely elucidated. Herein, we intend to explore the function and molecular mechanism of lncRNA...

    Authors: Binfeng Wang and Xiangwei Liu
    Citation: Advances in Rheumatology 2021 61:31
  5. The Functional Index for Hand Osteoarthritis (FIHOA) is a simple, reliable, and reproducible specific instrument to evaluate hand OA that can be applied both in clinical practice and research protocols. In ord...

    Authors: Francisco Vileimar Andrade de Azevedo, Hermano Alexandre Lima Rocha, Anamaria Jones, Jamil Natour and Francisco Airton Castro da Rocha
    Citation: Advances in Rheumatology 2021 61:30

    The Correction to this article has been published in Advances in Rheumatology 2021 61:37

  6. Familial Mediterranean fever (FMF) is an autoinflammatory disease characterized by recurrent episodes of fever and serositis. Sacroiliitis can be observed in some FMF patients. This study aimed to compare the ...

    Authors: Hülya Kaçmaz, Esin Aldemir, Ayşe Tanatar, Şerife Gül Karadağ, Mustafa Çakan, Hafize Emine Sönmez and Nuray Aktay Ayaz
    Citation: Advances in Rheumatology 2021 61:29
  7. Few studies have evaluated the relation of quality of life (QoL) with symptoms and disease activity in primary Sjögren’s syndrome (pSS). There is also scant information on the predictors of QoL in this populat...

    Authors: Laiza Hombre Dias, Samira Tatiyama Miyamoto, Raquel Altoé Giovelli, Caerê Iamonde Maciel de Magalhães and Valeria Valim
    Citation: Advances in Rheumatology 2021 61:28
  8. Systemic sclerosis (SSc) is a chronic autoimmune disease characterized by vasculopathy and fibrosis, which can be subclassified into diffuse cutaneous (dSSc) and limited cutaneous (lSSc) subtypes. Previous stu...

    Authors: Laiana Schneider, Natália Aydos Marcondes, Vanessa Hax, Isadora Flesch da Silva Moreira, Carolina Yuka Ueda, Rafaella Romeiro Piovesan, Ricardo Xavier and Rafael Chakr
    Citation: Advances in Rheumatology 2021 61:27
  9. The Val66Met polymorphism of the brain-derived neurotrophic factor (BDNF) gene is a potential biomarker of vulnerability to pain. Thus, the present study aimed to investigate the association of this polymorphi...

    Authors: Angela Shiratsu Yamada, Flavia Tasmim Techera Antunes, Camila Ferraz, Alessandra Hubner de Souza and Daniel Simon
    Citation: Advances in Rheumatology 2021 61:24
  10. Chronic prostatitis has been a common disease reported with high frequency in ankylosing spondylitis (AS) even from decades ago. Infectious (Chlamydia trachomatis) or non-infectious (uric acid) prostatitis can hy...

    Authors: Eduardo Deves, Rodrigo Novotny, Fernando Hartmann Barazzetti, Mara Cristina Scheffer, Letícia Kramer Pacheco, Adriana Fontes Zimmermann, Ivânio Alves Pereira, Maria Luiza Bazzo and Fabricio Souza Neves
    Citation: Advances in Rheumatology 2021 61:23
  11. Hepatitis B virus (HBV) reactivation consequent to immunosuppressive therapy is an increasingly prevalent problem with serious clinical implications. Treatment with biologic agents conduces to the loss of prot...

    Authors: Ming-Hui Hung, Ya-Chih Tien and Ying-Ming Chiu
    Citation: Advances in Rheumatology 2021 61:22
  12. The most important finding that affects the prognosis in Familial Mediterranean Fever is renal amyloidosis. The aim of the present study was to analyze neutrophil gelatinase-associated lipocalin levels in the ...

    Authors: Sinem Can Oksay, Hasan Dursun, Sebnem Tekin Neijmann and Sami Hatipoglu
    Citation: Advances in Rheumatology 2021 61:20
  13. This study identified whether Functional Index for Hand Osteoarthritis (FIHOA) is associated with pain, hand muscle strength, health-related quality of life, and radiographic severity in hand osteoarthritis (OA).

    Authors: Seong-Kyu Kim, Ui Hong Jung and Jung-Yoon Choe
    Citation: Advances in Rheumatology 2021 61:19
  14. To investigate the associations between sleep quality, fatigue, disease activity and depressive symptoms in women with rheumatoid arthritis (RA).

    Authors: Fernando Henrique Azevedo Lopes, Max Victor Carioca Freitas, Veralice Meireles Sales de Bruin and Pedro Felipe Carvalhedo de Bruin
    Citation: Advances in Rheumatology 2021 61:18
  15. Hyperhomocysteinemia is associated with autoimmune diseases such as ankylosing spondylitis (AS), systemic lupus erythematosus (SLE), and rheumatoid arthritis (RA). Current findings regarding plasma/serum homoc...

    Authors: Hui-hui Li, Xue-quan Li, Lin-tao Sai, Yi Cui, Jia-hui Xu, Chi Zhou, Jing Zheng, Xing-fu Li, Hua-xiang Liu and Ying-jie Zhao
    Citation: Advances in Rheumatology 2021 61:17
  16. Systemic sclerosis (SSc) is a clinically complex and challenging disease, that leads to skin fibrosis. Its most frequent complication is interstitial lung disease (ILD), which leads to a worse prognosis. In th...

    Authors: Marina Maria Vieira de Figueiredo Caldas, Kesley Pablo Morais de Azevedo, Ana Clara de França Nunes, Victor Hugo de Oliveira, Isac Davidson Santiago Fernandes Pimenta, Isabela Dantas Torres de Araújo, Francisco Alves Bezerra Neto, Ana Katherine da Silveira Gonçalves de Oliveira and Grasiela Piuvezam
    Citation: Advances in Rheumatology 2021 61:15
  17. The objective of this paper is to analyze the prices of biological drugs in the treatment of Rheumatoid Arthritis (RA) in three Latin American countries (Brazil, Colombia and Mexico), as well as in Spain and t...

    Authors: Gabriela Bittencourt Gonzalez Mosegui, Fernando Antõnanzas, Cid Manso de Mello Vianna and Paula Rojas
    Citation: Advances in Rheumatology 2021 61:14
  18. Psoriatic arthritis (PsA) is a multifaceted inflammatory disease that can cause joint destruction and impair quality of life. The Psoriatic Arthritis Quality of Life Questionnaire (PsAQoL) was the first diseas...

    Authors: Rafaela Silva Guimaraes Gonçalves, Alice Heaney, Stephen P. McKenna, Jonas Braynner Carvalho, Maria Eduarda Lima Vidal, Marina Coelho Mores de Brito and Angela Luzia Branco Pinto Duarte
    Citation: Advances in Rheumatology 2021 61:13
  19. Sickle cell disease (SCD) is an autosomal recessive genetic disease in which a mutation occurs in the β-globin chain gene, resulting in abnormal hemoglobin levels. In an environment with reduced oxygen concent...

    Authors: Taciana Fernandes Araújo Ferreira, Ana Paula Teixeira dos Santos, Alexandra Silva Leal, Gilberto de Araújo Pereira, Sheila Soares Silva and Helio Moraes-Souza
    Citation: Advances in Rheumatology 2021 61:11
  20. Fibromyalgia is a chronic pain disorder characterized by widespread musculoskeletal symptoms, primarily attributed to sensitization of somatosensory system carrying pain. Few reports have investigated the impa...

    Authors: Vikas Kumar Tiwari, Srishti Nanda, Suvercha Arya, Uma Kumar, Ratna Sharma, Senthil S. Kumaran and Renu Bhatia
    Citation: Advances in Rheumatology 2021 61:10
  21. In the past 20 years, hematopoietic stem cell transplantation (HSCT) has been investigated as treatment for systemic sclerosis (SSc). The goal of HSCT is to eradicate the autoreactive immune system, which is r...

    Authors: Álvaro Henrique-Neto, Marianna Yumi Kawashima Vasconcelos, Juliana Bernardes Elias Dias, Daniela Aparecida de Moraes, Maynara Santana Gonçalves, Djúlio César Zanin-Silva, Talita Graminha Zucoloto, Marília de Fátima Cirioli de Oliveira, Giuliana Martinelli Dotoli, Luiz Fernando Weffort, Vanessa Cristina Leopoldo and Maria Carolina Oliveira
    Citation: Advances in Rheumatology 2021 61:9
  22. Sjögren’s Syndrome compromises the exocrine function, producing xerostomia and xerophthalmia. It can appear as an isolated condition or associated with other autoimmune diseases (polyautoimmunity). The Unstimu...

    Authors: María Alejandra Martínez-Ceballos, Natalia Aguilera, Kenny Carolina Garzón-González, Jairo Cajamarca-Baron, Juan Pablo Alzate-Granados and Adriana Rojas-Villarraga
    Citation: Advances in Rheumatology 2021 61:8
  23. To compare the efficacy and safety of a new formulation of a fixed dose combination of glucosamine sulfate (GS; 1500 mg) and bovine chondroitin sulfate (CS; 1200 mg) versus the reference product (RP) in patien...

    Authors: Andrea Barranjard Vannucci Lomonte, Emerson Gimenez, Antônio Carlos da Silva, Sebastião Cezar Radominski, Morton Aaron Scheinberg, Antônio Carlos Ximenes and Cristiano Augusto de Freitas Zerbini
    Citation: Advances in Rheumatology 2021 61:7
  24. Complementary and alternative medicine (CAM) use is prevalent among patients living with arthritis. Such patients often seek information online, for the purpose of gaining a second opinion to their healthcare ...

    Authors: Jeremy Y. Ng, Alexandra Vacca and Tanya Jain
    Citation: Advances in Rheumatology 2021 61:6
  25. Abdominal symptoms in patients with primary Sjögren syndrome (pSS) are poorly documented. The objective of the study was to describe the abdominal symptoms of patients with pSS and to assess their association ...

    Authors: Simon Parreau, Jérémie Jacques, Stéphanie Dumonteil, Sylvain. Palat, Sophie Geyl, Guillaume Gondran, Holy Bezanahary, Eric Liozon, Julie Azaïs, Stéphanie Colombie, Marie-Odile Jauberteau, Véronique Loustaud-Ratti, Kim-Heang Ly and Anne-Laure Fauchais
    Citation: Advances in Rheumatology 2021 61:5
  26. Spondyloarthritis (SpA) is a group of chronic inflammatory systemic diseases characterized by axial and/or peripheral joints inflammation, as well as extra-articular manifestations. Over some decades, nonstero...

    Authors: Ricardo da Cruz Lage, Claudia Diniz Lopes Marques, Thauana Luiza Oliveira, Gustavo Gomes Resende, Charles Lubianca Kohem, Carla Gonçalves Saad, Antônio Carlos Ximenes, Célio Roberto Gonçalves, Washington Alves Bianchi, Eduardo de Souza Meirelles, Mauro Waldemar Keiserman, Adriano Chiereghin, Cristiano Barbosa Campanholo, André Marun Lyrio, Cláudia Goldenstein Schainberg, Lenise Brandao Pieruccetti…
    Citation: Advances in Rheumatology 2021 61:4
  27. Whole-body cryotherapy (WBC) has shown to be beneficial in the treatment of fibromyalgia (FM). There is cumulative evidence that cytokines play a crucial role in FM. It’s unknown whether clinical effects of WB...

    Authors: Philipp Klemm, Johanna Becker, Iris Aykara, Thomas Asendorf, Gabriel Dischereit, Elena Neumann, Ulf Müller-Ladner and Uwe Lange
    Citation: Advances in Rheumatology 2021 61:3
  28. Large epidemiologic and clinical estimates of spondyloarthritis (SpA) in Latin America are not available. In this narrative review, our goal was to descriptively summarize the prevalence and features of SpA in...

    Authors: Gustavo Citera, Wilson Bautista-Molano, Ingris Peláez-Ballestas, Valderilio F. Azevedo, Risto A. Perich, José A. Méndez-Rodríguez, Mariel S. Cutri and Cecilia E. Borlenghi
    Citation: Advances in Rheumatology 2021 61:2

    The Letter to this article has been published in Advances in Rheumatology 2021 61:26

  29. Modifiable cardiovascular risk factors (MCRFs), such as those related to aerobic capacity, muscle strength, physical activity, and body composition, have been poorly studied in Takayasu arteritis (TAK). Theref...

    Authors: Alexandre Moura dos Santos, Rafael Giovani Misse, Isabela Bruna Pires Borges, Bruno Gualano, Alexandre Wagner Silva de Souza, Liliam Takayama, Rosa Maria R. Pereira and Samuel Katsuyuki Shinjo
    Citation: Advances in Rheumatology 2021 61:1
  30. Systemic sclerosis (SSc) is an autoimmune disease characterized by fibrosis of skin and lung as well as involvement of kidney, gastrointestinal system and heart. Aetiology and exact mechanism of disease is poo...

    Authors: Tugce Emiroglu Gedik, Hamit Kucuk, Berna Goker, Seminur Haznedaroglu, Hatice Pasaoglu, Ozkan Varan, Mehmet Akif Ozturk, Ozge Tugce Pasaoglu and Abdurrahman Tufan
    Citation: Advances in Rheumatology 2020 60:54
  31. Adverse drug reactions (ADRs) are the sixth leading causes of death worldwide; monitoring them is fundamental, especially in patients with disorders like chronic rheumatic diseases (CRDs). The study aimed to d...

    Authors: Manar Amanouil Said, Liana Soido Teixeira e Silva, Aline Maria de Oliveira Rocha, Gustavo Guimarães Barreto Alves, Daniela Gerent Petry Piotto, Claudio Arnaldo Len and Maria Teresa Terreri
    Citation: Advances in Rheumatology 2020 60:53
  32. Gout is characterized by inflammatory arthritis with hyperuricaemia and deposition of monosodium urate (MSU) crystals in the joints. Several animal models have been proposed based on MSU crystals injection or ...

    Authors: Xiaoying Lin, Tiejuan Shao, Xianghui Wen, Mingzhu Wang, Chengping Wen and Zhixing He
    Citation: Advances in Rheumatology 2020 60:52
  33. The COVID-19 outbreak caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a global major concern. In this review, we addressed a theoretical model on immunopathogenesis associated...

    Authors: Bruno Bordallo, Mozart Bellas, Arthur Fernandes Cortez, Matheus Vieira and Marcelo Pinheiro
    Citation: Advances in Rheumatology 2020 60:50
  34. Psoriatic arthritis (PsA) is a chronic inflammatory disease of widely varying presentation, which determines functional and psychological impairment, with a high negative impact on patients’ quality of life.

    Authors: Elziane da Cruz Ribeiro e Souza, Sueli Coelho da Silva Carneiro, Michel Alexandre Yazbek, Rita de Cássia Menin, Cristiano Barbosa Campanholo, Jamille Nascimento Carneiro, Carlos Henrique Martis da Silva and Roberto Ranza
    Citation: Advances in Rheumatology 2020 60:49
  35. The reproducibility and reliability of the modified Rodnan’s Skin Score (mRSS) are debated due to investigator-related subjectivity. Here, we evaluate if durometry correlates with mRSS in patients with diffuse...

    Authors: Marília de Fátima Cirioli de Oliveira, Vanessa Cristina Leopoldo, Karla Ribeiro Costa Pereira, Daniela Aparecida de Moraes, Juliana Bernardes Elias Dias, Maynara Santana Gonçalves, Leandra Naíra Zambelli Ramalho, Bruna Nogueira dos Santos, Maria Carolina de Oliveira and Renata Cristina Campos Pereira Silveira
    Citation: Advances in Rheumatology 2020 60:48
  36. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Alex Domingos Reis, Cristiane Mudinutti, Murilo de Freitas Peigo, Lucas Lopes Leon, Lilian Tereza Lavras Costallat, Claudio Lucio Rossi, Sandra Cecília Botelho Costa and Sandra Helena Alves Bonon
    Citation: Advances in Rheumatology 2020 60:47

    The original article was published in Advances in Rheumatology 2020 60:42

  37. Chronic low back pain (CLBP) represents a problem in the occupational environment, often associated with disability, sick-leave demands, loss of productivity, anxiety, depression and high socioeconomic cost. T...

    Authors: Aloma A. Feitosa, Edson Amaro Junior, Liana Guerra Sanches, Eduardo Ferreira Borba, Liliana Lourenço Jorge and Ari Stiel Radu Halpern
    Citation: Advances in Rheumatology 2020 60:46
  38. Anti-ribosomal P (anti-Rib-P) antibody is a specific serological marker for systemic lupus erythematosus (SLE) and routinely tested by targeting the common epitope of three ribosomal proteins of P0, P1 and P2....

    Authors: Zhen-rui Shi, Yan-fang Han, Jing Yin, Yu-ping Zhang, Ze-xin Jiang, Lin Zheng, Guo-zhen Tan and Liangchun Wang
    Citation: Advances in Rheumatology 2020 60:45
  39. Methotrexate (MTX) intolerance is frequent, and its early identification may impact treatment, leading to timely changes in medication that may promote patient compliance and better control of rheumatoid arthr...

    Authors: Jéssica Martins Amaral, Maria José Menezes Brito and Adriana Maria Kakehasi
    Citation: Advances in Rheumatology 2020 60:43
  40. Human herpesviruses (HHVs) are responsible for a significant number of clinical manifestations in systemic lupus erythematous (SLE) patients. The aim of this study was to determine the frequency of active HHV ...

    Authors: Alex Domingos Reis, Cristiane Mudinutti, Murilo de Freitas Peigo, Lucas Lopes Leon, Lilian Tereza Lavras Costallat, Claudio Lucio Rossi, Sandra Cecília Botelho Costa and Sandra Helena Alves Bonon
    Citation: Advances in Rheumatology 2020 60:42

    The Correction to this article has been published in Advances in Rheumatology 2020 60:47

  41. Hand osteoarthritis (HOA) is a complex disorder with various subtypes characterized with predominance of different features. It is challenging to estimate the severity of hand disability in HOA, since contribu...

    Authors: Nurhan Güven, Fitnat Dinçer, Alp Çetin and Serdar Can Güven
    Citation: Advances in Rheumatology 2020 60:41
  42. It is known that physical activity and muscular performance are reduced in fibromyalgia (FM) syndrome. This study aims to compare the performance of trunk muscles in women with FM and healthy controls and eval...

    Authors: Cevriye Mülkoğlu, Sühan Taşkın, Seçil Vural, Başak Mansız Kaplan, Ahmet Buğra Selvi and Hakan Genç
    Citation: Advances in Rheumatology 2020 60:40
  43. Fibromyalgia (FM) is a musculoskeletal chronic pain syndrome that impacts negatively patient’s daily lives. Its pathogenesis is characterized by a complex relationship between biological and psychosocial facto...

    Authors: Camila Fernanda da Silveira Alves, Wolnei Caumo, Joana Morez Silvestri, Maxciel Zortea, Vinicius Souza dos Santos, Dayane Favarin Cardoso, Andrea Regner, Alessandra Hübner de Souza and Daniel Simon
    Citation: Advances in Rheumatology 2020 60:39

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