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[Highly accessed] Comparing the efficacy and safety of duloxetine and amitriptyline in the treatment of fibromyalgia: overview of systematic reviews

There is little agreement about which drug is more effective and safer. This study aimed to compare evidence of the efficacy and safety of duloxetine compared with amitriptyline in the treatment of adult patients with fibromyalgia. The results help guiding clinicians on the use of these drugs and provide information for public health decision-makers.

  1. Authors: Valderilio Feijó Azevedo, Igor Age Kos, Ana Beatriz Vargas-Santos, Geraldo da Rocha Castelar Pinheiro and Eduardo dos Santos Paiva

    Content type: Review

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Journal archives

Formerly named Revista Brasileira de Reumatologia, the journal is celebrating its 60th year of publication in 2020. Articles published prior to January 2018 are available here.

Aims and scope

Advances in Rheumatology is an international, open access journal publishing pre-clinical, translational and clinical studies on all aspects of paediatric and adult rheumatic diseases, including degenerative, inflammatory and autoimmune conditions. We welcome original research (including systematic reviews and meta-analyses), reviews, guidelines and letters arising from published material.

About the Editors-in-Chief

New Content ItemDr. Marcos Renato de Assis is Professor of Rheumatology at Marilia Medical School, Brazil. He completed his PhD in Rehabilitation at Federal University of São Paulo, in 2003, studying patients with fibromyalgia. He also has specialization in PM&R and acted as senior teaching assistant for a distance-learning training program on clinical research by Harvard Medical School (2010-2015). His interests are fibromyalgia, rheumatoid arthritis, spondyloarthritis, tools validation and distance learning.

New Content ItemDr. Simone Appenzeller is Associate Professor of Rheumatology at University of Campinas, Brazil, where she received her PhD, in 2006, investigating systemic lupus erythematosus. She did a postdoc at McGill University, Canada, and then at University of Stavanger, Norway. As a researcher, she uses neuroimaging to understand the role of the central nervous system in systemic lupus erythematosus.

About the Society

The Brazilian Society of Rheumatology (SBR) was founded in 1949 and its mission is to promote excellence in rheumatology by encouraging teaching, research and care, and contributing to the formulation of public policies aimed at the health and well-being of the rheumatic patients. SBR brings together Brazilian rheumatologists, disseminating the specialty, organizing courses and congresses, and fostering scientific research.

In 2018, the Society approved and published its Code of Ethics whose principles are intended to ensure its mission, vision, and values, according to its statuses and bylaws. Read the full document here.

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