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Fig. 3 | Advances in Rheumatology

Fig. 3

From: The effect of PD-1/PD-L1 signaling axis on the interaction between CD19+B cells and CD4+T cells in peripheral blood of patients with systemic lupus erythematosus

Fig. 3

Effect of activated CD19+BCs on the expression and proliferation of PD-L1 and PD-1 in CD4+TCs. (A) Representative histograms of PD-L1 expression on total CD19+BCs. (B) Expression (frequency, left panel, and MFI, right panel) of CD19+PD-L1+BCs. (C) Flow cytometry of the effects of activated CD19+BCs on the proliferation of CD4+TCs, and statistical results of the effects of activated CD19+BCs on the proliferation of CD4+TCs (D) and the expression of PD-L1 (E) and PD-1 (F). *P < 0.05, **P < 0.01, ***P < 0.001

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