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Table 1 Comparative analysis of clinical and serological data in 71 patients with Systemic Lupus Erythematosus (SLE) with early and late onset nephritis

From: Comparison of lupus patients with early and late onset nephritis: a study in 71 patients from a single referral center

  Total sample
N = 71
Early nephritis
N = 50 (70. 4%)
Late nephritis
N = 21 (29.6%)
P a
Ethnic background b Caucasians 27
Afrodescendants 44
Caucasians 16
Afrodescendants 34
Caucasians 11
Afrodescendants 10
0.64
Median age at SLE diagnosis (years) (IQR) 26.0 (21.0–38.0) 27 (21-40.2) 26 (21.0–37.0) 0.67
Median age at nephritis diagnosis (years) (IQR) 30.0 (23.0–42.0) 27.5 (21. 7-41.0) 35 (29. 5-43.5) 0.01
Female gender 62 (87. 3%) 43 (84. 3%) 19 (90. 4%) 0.71
Tobaco exposure 8 (11.2%) 4 (9%) 4 (19.0%) 0.22
Malar rash 30 (42.2%) 20 (40%) 10 (47.6%) 0.55
Discoid lesions 2 (2.8%) 0 2 (9.5%) 0.08
Photossensitivity 48 (67.6%) 32 (64%) 16 (76.1%) 0.72
Oral ulcers 35 (49.2%) 24 (48%) 11 (52. 3%) 0.73
Articular involvement 60 (84.5%) 40 (80%) 20 (95.2%) 0.15
Serositis 18 (25. 3%) 15 (30%) 3 (14.2%) 0.23
Psychosis 1 (1. 4%) 0 1 (4.7%) 0.29
Convulsions 6 (8. 4%) 6 (12%) 0 0.16
Hemolytic anemia 8 (11. 4%) 7 (14.2%) 1 (4.7%) 0.42
Leukopenia 25 (35.2%) 15 (30%) 10 (47.6%) 0.15
Lymphocytopenia 15 (21.1%) 11 (22%) 4 (19.0%) 1.00
Thrombocytopenia 2 (2.8%) 1 (2%) 1 (4.7%) 0.50
Anti-Ro (SS-A) 26 (36.6%) 19 (38%) 7 (33. 3%) 0.70
Anti-La (SS-B) 10 (14.0%) 7 (14%) 3 (14.2%) 1.00
Anti-RNP 13 (18. 3%) 7 (14%) 6 (28.5%) 0.14
Anti-Sm 13 (18. 3%) 8 (16%) 5 (23.8%) 0.50
Positive Coombs 6 (8. 4%) 5 (10%) 1 (4.7%) 0.66
Rheumatoid factor 6 (8. 4%) 6 (12%) 0 0.16
Anticardiolipin IgG 1 (1. 4%) 1 (2%) 0 1.00
Anticardiolipin IgM 2 (2.8%) 2 (4%) 0 1.00
Lupus anticoagulante 5 (7.0%) 3 (6%) 2 (9.5%) 0.62
Antiphospholipid antibody syndrome 5 (7.0%) 3 (6%) 2 (9.5%) 0.62
  1. a refers to early onset versus late onset; b- auto declared; IQR interquartile range, n number