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  1. To investigate the diagnostic performance of single-source dual-energy computed tomography (DECT) based on gemstone spectral imaging technology (including Discovery CT750HD and Revolution CT) in patients with ...

    Authors: Jin Shang, Xiao-Hu Li, Shu-Qin Lu, Yi Shang, Lu-Lu Li and Bin Liu

    Citation: Advances in Rheumatology 2021 61:36

    Content type: Research

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  2. Trunk pelvic dissociation is fundamental to the compensatory mechanism for muscle weakness during body bending. We carried out an early investigation of gait changes in a sample of community-dwelling women ≥60...

    Authors: Leda Magalhaes Oliveira, Suely Roizenblatt, Flavio Duarte Silva, Arnaldo Roizenblatt, Artur Rocha Correa Fernandes and Vera Lucia Szejnfeld

    Citation: Advances in Rheumatology 2021 61:35

    Content type: Research

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  3. Systemic sclerosis (SSc) is a chronic disease characterized by autoimmunity, vasculopathy, and visceral and cutaneous fibrosis. Vitamin D has several functions in the immunological system, and different studie...

    Authors: Laiana Schneider, Vanessa Hax, Odirlei Monticielo, Tamires Ferri Macedo, Roberta Kern Menna Barreto, Natália Aydos Marcondes and Rafael Chakr

    Citation: Advances in Rheumatology 2021 61:34

    Content type: Research

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  4. Vasculitis damage index (VDI) is a validated damage index for systemic vasculitis, and as Behçet’s disease is considered one of systemic vascular disease we aimed to study the relationship of the vasculitis da...

    Authors: Fatema T. Elgengehy, Sherif M. Gamal, Nesreen Sobhy, Ibrahem Siam, Ahmed M. Soliman, Ghada W. Elhady and Tamer A. Gheita

    Citation: Advances in Rheumatology 2021 61:33

    Content type: Research

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  5. To evaluate the perception of rheumatologists regarding the recommendations of the Brazilian Consensus for detection of Autoantibodies (BCA) on HEp-2 Cells by Indirect Immunofluorescence assay (IFA) and how BC...

    Authors: Isadora Carvalho Medeiros Francescantonio, Leandro Augusto Rodrigues dos Santos, Paulo Luiz Carvalho Francescantonio, Luiz Eduardo Coelho Andrade and Wilson de Melo Cruvinel

    Citation: Advances in Rheumatology 2021 61:32

    Content type: Research

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  6. Osteoarthritis (OA) is defined as a degenerative disease. Pivotal roles of long non-coding RNA (lncRNAs) in OA are widely elucidated. Herein, we intend to explore the function and molecular mechanism of lncRNA...

    Authors: Binfeng Wang and Xiangwei Liu

    Citation: Advances in Rheumatology 2021 61:31

    Content type: Research

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  7. The Functional Index for Hand Osteoarthritis (FIHOA) is a simple, reliable, and reproducible specific instrument to evaluate hand OA that can be applied both in clinical practice and research protocols. In ord...

    Authors: Francisco Vileimar Andrade de Azevedo, Hermano Alexandre Lima Rocha, Anamaria Jones, Jamil Natour and Francisco Airton Castro da Rocha

    Citation: Advances in Rheumatology 2021 61:30

    Content type: Research

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    The Correction to this article has been published in Advances in Rheumatology 2021 61:37

  8. Familial Mediterranean fever (FMF) is an autoinflammatory disease characterized by recurrent episodes of fever and serositis. Sacroiliitis can be observed in some FMF patients. This study aimed to compare the ...

    Authors: Hülya Kaçmaz, Esin Aldemir, Ayşe Tanatar, Şerife Gül Karadağ, Mustafa Çakan, Hafize Emine Sönmez and Nuray Aktay Ayaz

    Citation: Advances in Rheumatology 2021 61:29

    Content type: Research

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  9. Few studies have evaluated the relation of quality of life (QoL) with symptoms and disease activity in primary Sjögren’s syndrome (pSS). There is also scant information on the predictors of QoL in this populat...

    Authors: Laiza Hombre Dias, Samira Tatiyama Miyamoto, Raquel Altoé Giovelli, Caerê Iamonde Maciel de Magalhães and Valeria Valim

    Citation: Advances in Rheumatology 2021 61:28

    Content type: Research

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  10. Systemic sclerosis (SSc) is a chronic autoimmune disease characterized by vasculopathy and fibrosis, which can be subclassified into diffuse cutaneous (dSSc) and limited cutaneous (lSSc) subtypes. Previous stu...

    Authors: Laiana Schneider, Natália Aydos Marcondes, Vanessa Hax, Isadora Flesch da Silva Moreira, Carolina Yuka Ueda, Rafaella Romeiro Piovesan, Ricardo Xavier and Rafael Chakr

    Citation: Advances in Rheumatology 2021 61:27

    Content type: Research

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  11. The Val66Met polymorphism of the brain-derived neurotrophic factor (BDNF) gene is a potential biomarker of vulnerability to pain. Thus, the present study aimed to investigate the association of this polymorphi...

    Authors: Angela Shiratsu Yamada, Flavia Tasmim Techera Antunes, Camila Ferraz, Alessandra Hubner de Souza and Daniel Simon

    Citation: Advances in Rheumatology 2021 61:24

    Content type: Research

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  12. Chronic prostatitis has been a common disease reported with high frequency in ankylosing spondylitis (AS) even from decades ago. Infectious (Chlamydia trachomatis) or non-infectious (uric acid) prostatitis can hy...

    Authors: Eduardo Deves, Rodrigo Novotny, Fernando Hartmann Barazzetti, Mara Cristina Scheffer, Letícia Kramer Pacheco, Adriana Fontes Zimmermann, Ivânio Alves Pereira, Maria Luiza Bazzo and Fabricio Souza Neves

    Citation: Advances in Rheumatology 2021 61:23

    Content type: Research

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  13. Hepatitis B virus (HBV) reactivation consequent to immunosuppressive therapy is an increasingly prevalent problem with serious clinical implications. Treatment with biologic agents conduces to the loss of prot...

    Authors: Ming-Hui Hung, Ya-Chih Tien and Ying-Ming Chiu

    Citation: Advances in Rheumatology 2021 61:22

    Content type: Research

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  14. The most important finding that affects the prognosis in Familial Mediterranean Fever is renal amyloidosis. The aim of the present study was to analyze neutrophil gelatinase-associated lipocalin levels in the ...

    Authors: Sinem Can Oksay, Hasan Dursun, Sebnem Tekin Neijmann and Sami Hatipoglu

    Citation: Advances in Rheumatology 2021 61:20

    Content type: Research

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  15. This study identified whether Functional Index for Hand Osteoarthritis (FIHOA) is associated with pain, hand muscle strength, health-related quality of life, and radiographic severity in hand osteoarthritis (OA).

    Authors: Seong-Kyu Kim, Ui Hong Jung and Jung-Yoon Choe

    Citation: Advances in Rheumatology 2021 61:19

    Content type: Research

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  16. To investigate the associations between sleep quality, fatigue, disease activity and depressive symptoms in women with rheumatoid arthritis (RA).

    Authors: Fernando Henrique Azevedo Lopes, Max Victor Carioca Freitas, Veralice Meireles Sales de Bruin and Pedro Felipe Carvalhedo de Bruin

    Citation: Advances in Rheumatology 2021 61:18

    Content type: Research

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  17. Hyperhomocysteinemia is associated with autoimmune diseases such as ankylosing spondylitis (AS), systemic lupus erythematosus (SLE), and rheumatoid arthritis (RA). Current findings regarding plasma/serum homoc...

    Authors: Hui-hui Li, Xue-quan Li, Lin-tao Sai, Yi Cui, Jia-hui Xu, Chi Zhou, Jing Zheng, Xing-fu Li, Hua-xiang Liu and Ying-jie Zhao

    Citation: Advances in Rheumatology 2021 61:17

    Content type: Research

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  18. Systemic sclerosis (SSc) is a clinically complex and challenging disease, that leads to skin fibrosis. Its most frequent complication is interstitial lung disease (ILD), which leads to a worse prognosis. In th...

    Authors: Marina Maria Vieira de Figueiredo Caldas, Kesley Pablo Morais de Azevedo, Ana Clara de França Nunes, Victor Hugo de Oliveira, Isac Davidson Santiago Fernandes Pimenta, Isabela Dantas Torres de Araújo, Francisco Alves Bezerra Neto, Ana Katherine da Silveira Gonçalves de Oliveira and Grasiela Piuvezam

    Citation: Advances in Rheumatology 2021 61:15

    Content type: Research

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  19. The objective of this paper is to analyze the prices of biological drugs in the treatment of Rheumatoid Arthritis (RA) in three Latin American countries (Brazil, Colombia and Mexico), as well as in Spain and t...

    Authors: Gabriela Bittencourt Gonzalez Mosegui, Fernando Antõnanzas, Cid Manso de Mello Vianna and Paula Rojas

    Citation: Advances in Rheumatology 2021 61:14

    Content type: Review

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  20. Psoriatic arthritis (PsA) is a multifaceted inflammatory disease that can cause joint destruction and impair quality of life. The Psoriatic Arthritis Quality of Life Questionnaire (PsAQoL) was the first diseas...

    Authors: Rafaela Silva Guimaraes Gonçalves, Alice Heaney, Stephen P. McKenna, Jonas Braynner Carvalho, Maria Eduarda Lima Vidal, Marina Coelho Mores de Brito and Angela Luzia Branco Pinto Duarte

    Citation: Advances in Rheumatology 2021 61:13

    Content type: Research

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  21. Sickle cell disease (SCD) is an autosomal recessive genetic disease in which a mutation occurs in the β-globin chain gene, resulting in abnormal hemoglobin levels. In an environment with reduced oxygen concent...

    Authors: Taciana Fernandes Araújo Ferreira, Ana Paula Teixeira dos Santos, Alexandra Silva Leal, Gilberto de Araújo Pereira, Sheila Soares Silva and Helio Moraes-Souza

    Citation: Advances in Rheumatology 2021 61:11

    Content type: Research

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  22. Fibromyalgia is a chronic pain disorder characterized by widespread musculoskeletal symptoms, primarily attributed to sensitization of somatosensory system carrying pain. Few reports have investigated the impa...

    Authors: Vikas Kumar Tiwari, Srishti Nanda, Suvercha Arya, Uma Kumar, Ratna Sharma, Senthil S. Kumaran and Renu Bhatia

    Citation: Advances in Rheumatology 2021 61:10

    Content type: Research

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  23. In the past 20 years, hematopoietic stem cell transplantation (HSCT) has been investigated as treatment for systemic sclerosis (SSc). The goal of HSCT is to eradicate the autoreactive immune system, which is r...

    Authors: Álvaro Henrique-Neto, Marianna Yumi Kawashima Vasconcelos, Juliana Bernardes Elias Dias, Daniela Aparecida de Moraes, Maynara Santana Gonçalves, Djúlio César Zanin-Silva, Talita Graminha Zucoloto, Marília de Fátima Cirioli de Oliveira, Giuliana Martinelli Dotoli, Luiz Fernando Weffort, Vanessa Cristina Leopoldo and Maria Carolina Oliveira

    Citation: Advances in Rheumatology 2021 61:9

    Content type: Research

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  24. Sjögren’s Syndrome compromises the exocrine function, producing xerostomia and xerophthalmia. It can appear as an isolated condition or associated with other autoimmune diseases (polyautoimmunity). The Unstimu...

    Authors: María Alejandra Martínez-Ceballos, Natalia Aguilera, Kenny Carolina Garzón-González, Jairo Cajamarca-Baron, Juan Pablo Alzate-Granados and Adriana Rojas-Villarraga

    Citation: Advances in Rheumatology 2021 61:8

    Content type: Research

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  25. To compare the efficacy and safety of a new formulation of a fixed dose combination of glucosamine sulfate (GS; 1500 mg) and bovine chondroitin sulfate (CS; 1200 mg) versus the reference product (RP) in patien...

    Authors: Andrea Barranjard Vannucci Lomonte, Emerson Gimenez, Antônio Carlos da Silva, Sebastião Cezar Radominski, Morton Aaron Scheinberg, Antônio Carlos Ximenes and Cristiano Augusto de Freitas Zerbini

    Citation: Advances in Rheumatology 2021 61:7

    Content type: Research

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  26. Complementary and alternative medicine (CAM) use is prevalent among patients living with arthritis. Such patients often seek information online, for the purpose of gaining a second opinion to their healthcare ...

    Authors: Jeremy Y. Ng, Alexandra Vacca and Tanya Jain

    Citation: Advances in Rheumatology 2021 61:6

    Content type: Research

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  27. Abdominal symptoms in patients with primary Sjögren syndrome (pSS) are poorly documented. The objective of the study was to describe the abdominal symptoms of patients with pSS and to assess their association ...

    Authors: Simon Parreau, Jérémie Jacques, Stéphanie Dumonteil, Sylvain. Palat, Sophie Geyl, Guillaume Gondran, Holy Bezanahary, Eric Liozon, Julie Azaïs, Stéphanie Colombie, Marie-Odile Jauberteau, Véronique Loustaud-Ratti, Kim-Heang Ly and Anne-Laure Fauchais

    Citation: Advances in Rheumatology 2021 61:5

    Content type: Research

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  28. Spondyloarthritis (SpA) is a group of chronic inflammatory systemic diseases characterized by axial and/or peripheral joints inflammation, as well as extra-articular manifestations. Over some decades, nonstero...

    Authors: Ricardo da Cruz Lage, Claudia Diniz Lopes Marques, Thauana Luiza Oliveira, Gustavo Gomes Resende, Charles Lubianca Kohem, Carla Gonçalves Saad, Antônio Carlos Ximenes, Célio Roberto Gonçalves, Washington Alves Bianchi, Eduardo de Souza Meirelles, Mauro Waldemar Keiserman, Adriano Chiereghin, Cristiano Barbosa Campanholo, André Marun Lyrio, Cláudia Goldenstein Schainberg, Lenise Brandao Pieruccetti…

    Citation: Advances in Rheumatology 2021 61:4

    Content type: Position article and guidelines

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  29. Whole-body cryotherapy (WBC) has shown to be beneficial in the treatment of fibromyalgia (FM). There is cumulative evidence that cytokines play a crucial role in FM. It’s unknown whether clinical effects of WB...

    Authors: Philipp Klemm, Johanna Becker, Iris Aykara, Thomas Asendorf, Gabriel Dischereit, Elena Neumann, Ulf Müller-Ladner and Uwe Lange

    Citation: Advances in Rheumatology 2021 61:3

    Content type: Research

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  30. Large epidemiologic and clinical estimates of spondyloarthritis (SpA) in Latin America are not available. In this narrative review, our goal was to descriptively summarize the prevalence and features of SpA in...

    Authors: Gustavo Citera, Wilson Bautista-Molano, Ingris Peláez-Ballestas, Valderilio F. Azevedo, Risto A. Perich, José A. Méndez-Rodríguez, Mariel S. Cutri and Cecilia E. Borlenghi

    Citation: Advances in Rheumatology 2021 61:2

    Content type: Review

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    The Letter to this article has been published in Advances in Rheumatology 2021 61:26

  31. Modifiable cardiovascular risk factors (MCRFs), such as those related to aerobic capacity, muscle strength, physical activity, and body composition, have been poorly studied in Takayasu arteritis (TAK). Theref...

    Authors: Alexandre Moura dos Santos, Rafael Giovani Misse, Isabela Bruna Pires Borges, Bruno Gualano, Alexandre Wagner Silva de Souza, Liliam Takayama, Rosa Maria R. Pereira and Samuel Katsuyuki Shinjo

    Citation: Advances in Rheumatology 2021 61:1

    Content type: Research

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  32. Systemic sclerosis (SSc) is an autoimmune disease characterized by fibrosis of skin and lung as well as involvement of kidney, gastrointestinal system and heart. Aetiology and exact mechanism of disease is poo...

    Authors: Tugce Emiroglu Gedik, Hamit Kucuk, Berna Goker, Seminur Haznedaroglu, Hatice Pasaoglu, Ozkan Varan, Mehmet Akif Ozturk, Ozge Tugce Pasaoglu and Abdurrahman Tufan

    Citation: Advances in Rheumatology 2020 60:54

    Content type: Research

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  33. Adverse drug reactions (ADRs) are the sixth leading causes of death worldwide; monitoring them is fundamental, especially in patients with disorders like chronic rheumatic diseases (CRDs). The study aimed to d...

    Authors: Manar Amanouil Said, Liana Soido Teixeira e Silva, Aline Maria de Oliveira Rocha, Gustavo Guimarães Barreto Alves, Daniela Gerent Petry Piotto, Claudio Arnaldo Len and Maria Teresa Terreri

    Citation: Advances in Rheumatology 2020 60:53

    Content type: Research

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  34. Gout is characterized by inflammatory arthritis with hyperuricaemia and deposition of monosodium urate (MSU) crystals in the joints. Several animal models have been proposed based on MSU crystals injection or ...

    Authors: Xiaoying Lin, Tiejuan Shao, Xianghui Wen, Mingzhu Wang, Chengping Wen and Zhixing He

    Citation: Advances in Rheumatology 2020 60:52

    Content type: Research

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  35. The COVID-19 outbreak caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a global major concern. In this review, we addressed a theoretical model on immunopathogenesis associated...

    Authors: Bruno Bordallo, Mozart Bellas, Arthur Fernandes Cortez, Matheus Vieira and Marcelo Pinheiro

    Citation: Advances in Rheumatology 2020 60:50

    Content type: Review

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  36. Psoriatic arthritis (PsA) is a chronic inflammatory disease of widely varying presentation, which determines functional and psychological impairment, with a high negative impact on patients’ quality of life.

    Authors: Elziane da Cruz Ribeiro e Souza, Sueli Coelho da Silva Carneiro, Michel Alexandre Yazbek, Rita de Cássia Menin, Cristiano Barbosa Campanholo, Jamille Nascimento Carneiro, Carlos Henrique Martis da Silva and Roberto Ranza

    Citation: Advances in Rheumatology 2020 60:49

    Content type: Research

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  37. The reproducibility and reliability of the modified Rodnan’s Skin Score (mRSS) are debated due to investigator-related subjectivity. Here, we evaluate if durometry correlates with mRSS in patients with diffuse...

    Authors: Marília de Fátima Cirioli de Oliveira, Vanessa Cristina Leopoldo, Karla Ribeiro Costa Pereira, Daniela Aparecida de Moraes, Juliana Bernardes Elias Dias, Maynara Santana Gonçalves, Leandra Naíra Zambelli Ramalho, Bruna Nogueira dos Santos, Maria Carolina de Oliveira and Renata Cristina Campos Pereira Silveira

    Citation: Advances in Rheumatology 2020 60:48

    Content type: Research

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  38. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Alex Domingos Reis, Cristiane Mudinutti, Murilo de Freitas Peigo, Lucas Lopes Leon, Lilian Tereza Lavras Costallat, Claudio Lucio Rossi, Sandra Cecília Botelho Costa and Sandra Helena Alves Bonon

    Citation: Advances in Rheumatology 2020 60:47

    Content type: Correction

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    The original article was published in Advances in Rheumatology 2020 60:42

  39. Chronic low back pain (CLBP) represents a problem in the occupational environment, often associated with disability, sick-leave demands, loss of productivity, anxiety, depression and high socioeconomic cost. T...

    Authors: Aloma A. Feitosa, Edson Amaro Junior, Liana Guerra Sanches, Eduardo Ferreira Borba, Liliana Lourenço Jorge and Ari Stiel Radu Halpern

    Citation: Advances in Rheumatology 2020 60:46

    Content type: Research

    Published on:

  40. Anti-ribosomal P (anti-Rib-P) antibody is a specific serological marker for systemic lupus erythematosus (SLE) and routinely tested by targeting the common epitope of three ribosomal proteins of P0, P1 and P2....

    Authors: Zhen-rui Shi, Yan-fang Han, Jing Yin, Yu-ping Zhang, Ze-xin Jiang, Lin Zheng, Guo-zhen Tan and Liangchun Wang

    Citation: Advances in Rheumatology 2020 60:45

    Content type: Research

    Published on:

  41. Methotrexate (MTX) intolerance is frequent, and its early identification may impact treatment, leading to timely changes in medication that may promote patient compliance and better control of rheumatoid arthr...

    Authors: Jéssica Martins Amaral, Maria José Menezes Brito and Adriana Maria Kakehasi

    Citation: Advances in Rheumatology 2020 60:43

    Content type: Research

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  42. Hand osteoarthritis (HOA) is a complex disorder with various subtypes characterized with predominance of different features. It is challenging to estimate the severity of hand disability in HOA, since contribu...

    Authors: Nurhan Güven, Fitnat Dinçer, Alp Çetin and Serdar Can Güven

    Citation: Advances in Rheumatology 2020 60:41

    Content type: Research

    Published on:

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