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  1. To determine the burden of Rheumatoid Arthritis (RA) on patients’ work productivity and health related quality of life (HRQoL), and examine the influence of several exposure variables; to analyze the progressi...

    Authors: Ricardo Machado Xavier, Cristiano Augusto Freitas Zerbini, Daniel Feldman Pollak, Jorge Luis Alberto Morales-Torres, Philippe Chalem, José Fernando Molina Restrepo, Javier Arnaldo Duhau, Jacqueline Rodríguez Amado, Maurício Abello, Maria Celina de la Vega, Adriana Pérez Dávila, Priscila Martin Biegun, Maysa Silva Arruda and Cesar Ramos-Remus
    Citation: Advances in Rheumatology 2019 59:47
    Content type: Research Published on:

  2. Osteoporosis is a major healthcare concern in Latin America. Factors such as changing demographics, fragmented healthcare systems, and financial considerations may result in a huge increase in the burden of os...

    Authors: Joao L. Cunha-Borges, Guillermo Meléndez Mier, Noemí Casas, Adriana Medina, Jose Fernando Molina, Maria Laura García, Lindomar Guimarães Oliveria, Marcela S. Caselato, Angélica C. Cruz, Vanessa Ippolito and Sandra Flórez
    Citation: Advances in Rheumatology 2019 59:46
    Content type: Research Published on:

  4. Rheumatoid arthritis (RA) is a well-documented independent risk factor for cardiovascular disease. Obesity may provide an additional link between inflammation and accelerated atherosclerosis in RA.

    Authors: Maria Fernanda Brandão de Resende Guimarães, Carlos Ewerton Maia Rodrigues, Kirla Wagner Poti Gomes, Carla Jorge Machado, Claiton Viegas Brenol, Susana Ferreira Krampe, Nicole Pamplona Bueno de Andrade and Adriana Maria Kakehasi
    Citation: Advances in Rheumatology 2019 59:44
    Content type: Research Published on:

  5. The Indian Takayasu Clinical Activity Score (ITAS2010) was developed in 2010 as an assessment tool for disease activity in patients with Takayasu arteritis (TA). It has since been widely used in different stud...

    Authors: Scheila Fritsch, Rafaela Martinez Copes, Bruna Savioli, Mariana Freitas de Aguiar, Rozana Mesquita Ciconelli, Valderílio Feijó Azevedo and Alexandre W. S. de Souza
    Citation: Advances in Rheumatology 2019 59:43
    Content type: Research Published on:

  6. This research is recommended by the Myopathy Committee of the Brazilian Society of Rheumatology for the investigation and diagnosis of systemic autoimmune myopathies.

    Authors: Fernando Henrique Carlos de Souza, Daniel Brito de Araújo, Verônica Silva Vilela, Ricardo Santos Simões, Wanderley Marques Bernardo, Thais Amanda Frank, Bernardo Matos da Cunha and Samuel Katsuyuki Shinjo
    Citation: Advances in Rheumatology 2019 59:42
    Content type: Position article and guidelines Published on:

  7. Nail involvement has been described as a key clinical feature for both psoriasis (PsO) and psoriatic arthritis (PsA) and is an important risk factor in PsA. Thus, early diagnosis of nail involvement may be ess...

    Authors: José Alexandre Mendonça, Sibel Zehra Aydin and Maria-Antonietta D’Agostino
    Citation: Advances in Rheumatology 2019 59:41
    Content type: Review Published on:

  8. Rheumatoid arthritis (RA) is known to be associated with coronary artery diseases (CAD). Previous studies of the association between RA and CAD were reported mainly in non-Asian groups. We aimed to examine the...

    Authors: Tae Hyub Lee, Gwan Gyu Song, Sung Jae Choi, Hongdeok Seok and Jae Hyun Jung
    Citation: Advances in Rheumatology 2019 59:40
    Content type: Research Published on:

  9. To evaluate the efficacy and safety of prolotherapy with hypertonic dextrose in patients with knee osteoarthritis. A systematic search was performed in electronic databases including PUBMED, SCIELO, DIALNET an...

    Authors: Pedro Iván Arias-Vázquez, Carlos Alfonso Tovilla-Zárate, Blanca Gabriela Legorreta-Ramírez, Wajid Burad Fonz, Dory Magaña-Ricardez, Thelma Beatriz González-Castro, Isela Esther Juárez-Rojop and María Lilia López-Narváez
    Citation: Advances in Rheumatology 2019 59:39
    Content type: Review Published on:

  10. SLE is a systemic autoimmune disease generally affecting woman in the reproductive age. It is associated with an altered level of Tregs and oxidative stress while an increase in Tregs, and different antioxidan...

    Authors: Naveet Pannu, Rashmi Singh, Sukriti Sharma, Seema Chopra and Archana Bhatnagar
    Citation: Advances in Rheumatology 2019 59:38
    Content type: Research Published on:

  11. Benzbromarone is a uricosuric drug that has been used in the treatment of gout over the last 30 years. Due to its potent inhibition of the dominant apical (luminal) urate exchanger in the human proximal tubule...

    Authors: Valderilio Feijó Azevedo, Igor Age Kos, Ana Beatriz Vargas-Santos, Geraldo da Rocha Castelar Pinheiro and Eduardo dos Santos Paiva
    Citation: Advances in Rheumatology 2019 59:37
    Content type: Review Published on:

  12. Complement component 4 (C4) gene copy number (GCN) affects the susceptibility to systemic lupus erythematosus (SLE) in different populations, however the possible phenotype significance remains to be determine...

    Authors: Kaline Medeiros Costa Pereira, Sandro Perazzio, Atila Granado A. Faria, Eloisa Sa Moreira, Viviane C. Santos, Marcelle Grecco, Neusa Pereira da Silva and Luis Eduardo Coelho Andrade
    Citation: Advances in Rheumatology 2019 59:36
    Content type: Research Published on:

  13. The panniculitides remain as one of the most challenging areas for clinicians, as they comprise a heterogeneous group of inflammatory diseases involving the subcutaneous fat with potentially-shared clinical an...

    Authors: Thâmara Cristiane Alves Batista Morita, Gabriela Franco Sturzeneker Trés, Maria Salomé Cajas García, Ilana Halpern, Paulo Ricardo Criado and Jozelio Freire de Carvalho
    Citation: Advances in Rheumatology 2019 59:35
    Content type: Review Published on:

  14. Systemic lupus erythematosus (SLE) is a multi-systemic, chronic inflammatory disease of autoimmune nature, which can impair performance in daily life activities, causing to a compromised quality of life. Thus,...

    Authors: Tassia Catiuscia da Hora, Kelly Lima and Roberto Rodrigues Bandeira Tosta Maciel
    Citation: Advances in Rheumatology 2019 59:34
    Content type: Research Published on:

  16. Juvenile idiopathic arthritis (JIA) is a chronic inflammatory disease that affects children and adolescents. Its prevalence varies greatly from one study to another according to the population and methodology....

    Authors: Vânia Schinzel, Simone Guerra Lopes da Silva, Maria Teresa Terreri and Claudio Arnaldo Len
    Citation: Advances in Rheumatology 2019 59:32
    Content type: Research Published on:

  18. Adaptive immune cells, including CD4+CD69+ and CD4+CD25+FoxP3+ regulatory T (Treg) cells, are important for maintaining immunological tolerance. In human systemic lupus erythematosus (SLE), CD4+CD25+FoxP3+ Treg c...

    Authors: Tatiana Vasconcelos Peixoto, Solange Carrasco, Domingos Alexandre Ciccone Botte, Sergio Catanozi, Edwin Roger Parra, Thaís Martins Lima, Natasha Ugriumov, Francisco Garcia Soriano, Suzana Beatriz Verissímo de Mello, Caio Manzano Rodrigues and Cláudia Goldenstein-Schainberg
    Citation: Advances in Rheumatology 2019 59:30
    Content type: Research Published on:

  19. Describe the clinical and epidemiologic characteristics of patients with systemic lupus erythematosus (SLE) admitted to the intensive care unit (ICU).

    Authors: Maria Fernanda Alvarez Barreneche, William Dario Mcewen Tamayo, Daniel Montoya Roldan, Libia Maria Rodriguez Padilla, Carlos Jaime Velasquez Franco and Miguel Antonio Mesa Navas
    Citation: Advances in Rheumatology 2019 59:29
    Content type: Research Published on:

  20. The V Brazilian Consensus for determination of autoantibodies against cellular constituents on HEp-2 cells, held in Brasilia (DF, Brazil) on August 27, 2016, discussed the harmonization between the Brazilian C...

    Authors: Wilson de Melo Cruvinel, Luis Eduardo Coelho Andrade, Carlos Alberto von Mühlen, Alessandra Dellavance, Antônio Carlos Ximenes, Carlos David Bichara, Cleonice Bueno, Cristóvão Luis Pitangueira Mangueira, Eloísa Bonfá, Fabiano de Almeida Brito, Fernanda Bull Flumian, Glaucielen Gomes da Silva, Jozelia Rêgo, Lisiane Maria Ericoni dos Anjos, Natasha Slhessarenko, Sandra Gofinet Pasoto…
    Citation: Advances in Rheumatology 2019 59:28
    Content type: Position article and guidelines Published on:

    The Correction to this article has been published in Advances in Rheumatology 2020 60:6

  22. Imbalance and disfuntion in regulatory T-cells (Tregs) and IL-17 producer lymphocytes (Th17) have been implicated in the pathogenesis of rheumatoid arthritis (RA). Gray scale synovial proliferation (GS), power...

    Authors: Aline Defaveri do Prado, Melissa Cláudia Bisi, Deise Marcela Piovesan, Markus Bredemeier, Talita Siara Baptista, Laura Petersen, Moises Evandro Bauer, Inês Guimarães da Silveira, José Alexandre Mendonça and Henrique Luiz Staub
    Citation: Advances in Rheumatology 2019 59:26
    Content type: Research Published on:

  23. Osteoarthritis (OA) is a major musculoskeletal disease with high prevalence in the elderly. The study of genetic polymorphisms of inflammatory mediators involved in OA may contribute to the elucidation of the ...

    Authors: Marcos Tadeu Parron Fernandes, Karen Barros Parron Fernandes, Fernanda Freitas Anibal, Walquíria Shimoya-Bittencourt, Viviane Martins Santos, Priscila Daniele de Oliveira Perrucini and Regina Célia Poli-Frederico
    Citation: Advances in Rheumatology 2019 59:25
    Content type: Research Published on:

  24. Though gout is more prevalent in men than women, it remains unclear whether gender influences risk factors for incident gout. We aimed to systematically review all cohort studies examining risk factors for the...

    Authors: Peter L. Evans, James A. Prior, John Belcher, Charles A. Hay, Christian D. Mallen and Edward Roddy
    Citation: Advances in Rheumatology 2019 59:24
    Content type: Research Published on:

  25. The presence of enthesitis is associated with higher disease activity, more disability and incapacity to work and a poorer quality of life in spondyloarthritis (SpA). There is currently no consensus on which c...

    Authors: Penélope Esther Palominos, Ana Paula Beckhauser de Campos, Sandra Lúcia Euzébio Ribeiro, Ricardo Machado Xavier, Jady Wroblewski Xavier, Felipe Borges de Oliveira, Bruno Guerra, Carla Saldanha, Aline Castello Branco Mancuso, Charles Lubianca Kohem, Andrese Aline Gasparin and Percival Degrava Sampaio-Barros
    Citation: Advances in Rheumatology 2019 59:23
    Content type: Research Published on:

  27. The Henoch-Schönlein Purpura (HSP) orIgA vasculitis is the most common vasculitis of childhood and may occur with renal involvement, with hematuria and / or proteinuria, and may cause severe and non-reversible...

    Authors: Vânia Schinzel, Jade Dib Fernandez, Gleice Clemente, Melissa Mariti Fraga, Maria Cristina Andrade, Claudio Arnaldo Len and Maria Teresa Terreri
    Citation: Advances in Rheumatology 2019 59:21
    Content type: Research Published on:

  28. To date there are no specific classification criteria for childhood-onset systemic lupus erythematosus (cSLE). This study aims to compare the performance among the American College of Rheumatology (ACR) 1997, ...

    Authors: Adriana Rodrigues Fonseca, Marta Cristine Felix Rodrigues, Flavio Roberto Sztajnbok, Marcelo Gerardin Poirot Land and Sheila Knupp Feitosa de Oliveira
    Citation: Advances in Rheumatology 2019 59:20
    Content type: Research Published on:

  29. To evaluate the frequency of anti-collagen type V in humans with early systemic sclerosis (SSc) compared to defined SSc patients and healthy controls, since collagen type V was shown to be overexpressed in ear...

    Authors: Michelle R Ugolini-Lopes, Elenice Mantovani, Virgínia Lucia N Bonoldi, Ana Cristina de Medeiros Ribeiro, Eloisa Bonfá, Natalino Yoshinari and Danieli Andrade
    Citation: Advances in Rheumatology 2019 59:19
    Content type: Research Published on:

  31. In Brazil, we are facing an alarming epidemic scenario of Yellow fever (YF), which is reaching the most populous areas of the country in unvaccinated people. Vaccination is the only effective tool to prevent Y...

    Authors: Gecilmara Salviato Pileggi, Licia Maria Henrique Da Mota, Adriana Maria Kakehasi, Alexandre Wagner De Souza, Aline Rocha, Ana Karla Guedes de Melo, Caroline Araujo M. da Fonte, Cecilia Bortoletto, Claiton Viegas Brenol, Claudia Diniz Lopes Marques, Cyrla Zaltman, Eduardo Ferreira Borba, Enio Ribeiro Reis, Eutilia Andrade Medeiros Freire, Evandro Mendes Klumb, Georges Basile Christopoulos…
    Citation: Advances in Rheumatology 2019 59:17
    Content type: Position article and guidelines Published on:

  32. Adequate nutrition, including intake of dietary calcium and vitamin D, is important to maintain bone health. Evidence suggests that a deficiency in micronutrients may contribute to bone loss during aging and e...

    Authors: Melissa Morimoto, Nitin Shivappa, Patricia de Souza Genaro, Lígia Araújo Martini, Natielen Jacques Schuch, James R. Hebert and Marcelo Medeiros Pinheiro
    Citation: Advances in Rheumatology 2019 59:16
    Content type: Research Published on:

  33. Rheumatoid arthritis is a risk factor for early mortality due to cardiovascular disease. Interleukin-33 appears to protect against the development of atherosclerosis. The purpose of this study was to investiga...

    Authors: Maria Raquel Costa Pinto, Adriana Maria Kakehasi, Adriano José Souza, Wilson Campos Tavares Jr, Monaliza Angela Rocha, Cyntia Gabriele Michel Cardoso Trant and Marcus Vinicius Andrade
    Citation: Advances in Rheumatology 2019 59:15
    Content type: Research Published on:

  34. Digital ulcers (DUs) represent a frequent complication of systemic sclerosis (SSc). The aim of this study was to evaluate clinical, serological and capillaroscopy features that are associated with DUs in patie...

    Authors: Alex Magno Coelho Horimoto, Albert Schiaveto de Souza, Silvia Helena Rodrigues and Cristiane Kayser
    Citation: Advances in Rheumatology 2019 59:14
    Content type: Research Published on:

  35. To evaluate sexual function female adolescents and young adults with juvenile idiopathic arthritis (JIA) and healthy controls.

    Authors: Ana Claudia Pitta, Gabriela Ribeiro Viola Ferreira, Renato Bussadori Tomioka, Daniela Mencaroni Rodrigues Lourenço, Katia Kozu, Nadia Emi Aikawa, Adriana Maluf Elias Sallum, Lucia Maria Arruda Campos, Carmita Helena Najjar Abdo, Rosa Maria Rodrigues Pereira, Edmund Chada Baracat, Eloisa Bonfá and Clovis Artur Silva
    Citation: Advances in Rheumatology 2019 59:13
    Content type: Research Published on:

  36. Cytomegalovirus (CMV) is an opportunistic pathogen causing reactivation and disease in Systemic Lupus Erythematosus (SLE) patients. This study aims to systematically review the literature for risk factors asso...

    Authors: Hui Min Charlotte Choo, Wen Qi Cher, Yu Heng Kwan and Warren Weng Seng Fong
    Citation: Advances in Rheumatology 2019 59:12
    Content type: Review Published on:

  38. Anti-nucleosome and anti-C1q antibodies demonstrated an association with the development of glomerulonephritis in systemic lupus erythematosus (SLE). Some investigators have proposed that monitoring anti-C1q a...

    Authors: Imman Mokhtar Metwally, Nahla Naeem Eesa, Mariam Halim Yacoub and Rabab Mahmoud Elsman
    Citation: Advances in Rheumatology 2019 59:10
    Content type: Research Published on:

  39. Ankylosing spondylitis (AS) is a chronic inflammatory disease characterized by axial arthritis. The genetic–environmental factors seem to be involved in the pathogenesis of the disease and the disease debilita...

    Authors: Narjes Soleimanifar, Mohammad Hossein Nicknam, Katayoon Bidad, Ahmad Reza Jamshidi, Mahdi Mahmoudi, Shayan Mostafaei, Zahra Hosseini-khah and Behrouz Nikbin
    Citation: Advances in Rheumatology 2019 59:9
    Content type: Research Published on:

  40. In recent decades, obesity has become a public health problem in many countries. The objective of this study was to evaluate the main joint and extra-articular manifestations related to spondyloarthritis (SpA)...

    Authors: Thauana Luiza de Oliveira, Hilton Telles Libanori and Marcelo M. Pinheiro
    Citation: Advances in Rheumatology 2019 59:8
    Content type: Research Published on:

  41. Musculoskeletal pain is a constant complaint in pediatric practice. The pain may be related to a number of organic diseases and / or be part of the amplified musculoskeletal pain syndromes. Idiopathic musculoskel...

    Authors: Maria da Conceição Costa, Jamil Natour, Hilda A. V. Oliveira, Maria Teresa Terreri and Claudio A. Len
    Citation: Advances in Rheumatology 2019 59:7
    Content type: Research Published on:

  42. Recommendations of the Myopathy Committee of the Brazilian Society of Rheumatology for the management and therapy of systemic autoimmune myopathies (SAM).

    Authors: Fernando Henrique Carlos de Souza, Daniel Brito de Araújo, Verônica Silva Vilela, Mailze Campos Bezerra, Ricardo Santos Simões, Wanderley Marques Bernardo, Renata Miossi, Bernardo Matos da Cunha and Samuel Katsuyuki Shinjo
    Citation: Advances in Rheumatology 2019 59:6
    Content type: Position article and guidelines Published on:

  43. Nailfold capillaroscopy (NFC) is a reproducible, simple, low-cost, and safe imaging technique used for morphological analysis of nail bed capillaries. It is considered to be extremely useful for the investigat...

    Authors: Cristiane Kayser, Markus Bredemeier, Maria Teresa Caleiro, Karina Capobianco, Tatiana Melo Fernandes, Sheila Márcia de Araújo Fontenele, Eutilia Freire, Lilian Lonzetti, Renata Miossi, Juliana Sekiyama and Carolina de Souza Müller
    Citation: Advances in Rheumatology 2019 59:5
    Content type: Position article and guidelines Published on:

  44. Systemic Lupus Erythematosus (SLE) is an autoimmune disease which impairs the quality of life. The objective of study was to evaluate the effectiveness of Brief Group Psychoanalytic Psychotherapy to improve qu...

    Authors: Céu Tristão Martins Conceição, Ivone Minhoto Meinão, José Atilio Bombana and Emília Inoue Sato
    Citation: Advances in Rheumatology 2019 59:4
    Content type: Research Published on:

  45. To evaluate prevalence, clinical manifestations, laboratory abnormalities, treatment and outcome in a multicenter cohort of childhood-onset systemic lupus erythematosus (cSLE) patients with and without pannicu...

    Authors: Mônica Verdier, Pedro Anuardo, Natali Weniger Spelling Gormezano, Ricardo Romiti, Lucia Maria Arruda Campos, Nadia Emi Aikawa, Rosa Maria Rodrigues Pereira, Maria Teresa Terreri, Claudia Saad Magalhães, Juliana C. O. A. Ferreira, Marco Felipe Castro Silva, Mariana Ferriani, Ana Paula Sakamoto, Virginia Paes Leme Ferriani, Maraísa Centeville, Juliana Sato…
    Citation: Advances in Rheumatology 2019 59:3
    Content type: Research Published on:

  46. Rheumatoid arthritis (RA) is an autoimmune/inflammatory disease affecting 0.5 to 1% of adults worldwide and frequently leads to joint destruction and disability. Early diagnosis and early and effective therapy...

    Authors: Sara de Brito Rocha, Danielle Cristiane Baldo and Luis Eduardo Coelho Andrade
    Citation: Advances in Rheumatology 2019 59:2
    Content type: Review Published on:

  47. Pulmonary arterial hypertension (PAH) is a rare and severe complication of systemic lupus erythematosus (SLE). This study aimed to evaluate clinical and laboratory risk factors associated with PAH in SLE patie...

    Authors: Juliana Fernandes Sarmento Donnarumma, Eloara Vieira Machado Ferreira, Jaquelina Ota-Arakaki and Cristiane Kayser
    Citation: Advances in Rheumatology 2019 59:1
    Content type: Research article Published on:

  48. To evaluate autoimmune hepatitis (AIH) in a multicenter cohort of childhood-onset systemic lupus erythematosus (cSLE) patients.

    Authors: Verena A. Balbi, Bárbara Montenegro, Ana C. Pitta, Ana R. Schmidt, Sylvia C. Farhat, Laila P. Coelho, Juliana C. O. Ferreira, Rosa M. R. Pereira, Maria T. Terreri, Claudia Saad-Magalhães, Nadia E. Aikawa, Ana P. Sakamoto, Kátia Kozu, Lucia M. Campos, Adriana M. Sallum, Virginia P. Ferriani…
    Citation: Advances in Rheumatology 2018 58:43
    Content type: Research Published on:

  49. It has long been established that obesity plays a positive role against osteoporosis (OP) and low-impact fractures (Fx). However, more recent data has shown higher fracture risk in obese individuals. The aim o...

    Authors: Bruna Aurora Nunes Cavalcante Castro, Edgard Torres dos Reis Neto, Vera Lucia Szejnfeld, Jacob Szejnfeld, Valdecir Marvulle and Marcelo de Medeiros Pinheiro
    Citation: Advances in Rheumatology 2018 58:42
    Content type: Research Published on:

  50. To compare the efficacy and safety of a new fixed dose combination of glucosamine sulfate and chondroitin sulfate capsules (GS/CS) versus the fixed dose combination of glucosamine hydrochloride and chondroitin...

    Authors: Andrea Barranjard Vannucci Lomonte, José Alexandre Mendonça, Gilberto de Castro Brandão and Marise Lazaretti Castro
    Citation: Advances in Rheumatology 2018 58:41
    Content type: Research Published on:
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Advances in Rheumatology

ISSN: 2523-3106