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Fig. 1 | Advances in Rheumatology

Fig. 1

From: Inflammatory cytokines and their potential role in Sjogren’s syndrome risk: insights from a mendelian randomization study

Fig. 1

Diagram of the MR analysis. Assumption 1, genetic instruments are strongly associated with the exposures of interest; Assumption 2, genetic instruments are independent of confounding factors; Assumption 3, genetic instruments are not associated with outcome and affect outcome only via exposures. IVW, inverse variance weighted; LD, linkage disequilibrium; LOO analysis, leave-one-out analysis; WMedine, weighted medine; SNPs, single nucleotide polymorphisms; WM, weighted mode

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Advances in Rheumatology

ISSN: 2523-3106