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Table 1 Synovial histology of zymosan arthritis following MgCl2 administration

From: Systemic and local antiinflammatory effect of magnesium chloride in experimental arthritis

Group

Cell

Infiltration

Synovial

Proliferation

Naïve

0 (0.0–0.0)

0 (0.0–1.0)

Control

2.0* (2.0–3.0)

1.0* (1.0–3.0)

MgCl (p.o.)

1.5* (1.0–2.0)

0.5# (0.0–1.0)

MgCl (i.a.)

2.0* (1.0–2.0)

0.5 (0.0–1.0)

  1. Mice (n = 6/ group) received (90 mg/kg p.o or 500 µg intra-articular, i.a.) or saline i.a. (control) 30 min prior to 0.1 mg/25µL zymosan i.a. Naive mice received saline. Animals were killed under anestesia at 6 h. Results represent synovial histopathology scores (median; range). * p < 0.05 compared to naive and # p < 0.05 compared to control
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Advances in Rheumatology

ISSN: 2523-3106