Table 4 Bivariate hazard ratios from Cox regression analysis evaluating various factors’ influence on time from ILD diagnosis to death

Age (per SD)

1.95

1.11–3.42

0.02

Female

0.18

0.07–0.50

0.001

Hispanic ethnicity

2.21

0.69–7.10

0.18

Former or active smoker

1.37

0.51–3.65

0.53

Pulmonary hypertension

2.32

0.86–6.25

0.10

FVC predicted, n (%)

 Mild(> 76.9%)

1 (ref)

 Moderate(64.3–76.8%)

0.55

0.09–3.29

0.51

 Severe(< 64.2%)

1.13

0.29–4.37

0.86

DLCo, predicted, n (%)

 Normal/Mild

1 (ref)

 Moderate

0.78

0.13–4.69

0.79

 Severe

2.45

0.59–10.27

0.22

NSIP ILD pattern

0.47

0.13–1.66

0.24

UIP ILD pattern

1.68

0.63–4.52

0.30

Immunosuppression

1.08

0.31–3.78

0.91

Transplant referral

2.12

0.67–6.70

0.20

CTD Subtype

 RA^*

2.05

0.76–5.52

0.16

 Systemic Sclerosis

1.20

0.34–4.24

0.77

 Idiopathic Inflammatory Myositis

1.08

0.31–3.84

0.90

 Others (Spondylarthritis, ANCA vasculitis)

4.22

0.94–18.96

0.06

 SLE

0.58

0.08–4.43

0.60