Table 1 Comparative baseline characteristics of the entire cohort, hospitalized, and non-hospitalized CTD-ILD patients. Characteristics include demographics, lung function, radiographic patterns, and clinical interventions
Characteristic | Entire Cohort (n = 96) | Patients with CTD-ILD and hospitalization (n = 73) | Patients with CTD-ILD and no hospitalization (n = 23) | P-value |
|---|---|---|---|---|
Age, mean ± SD | 54.15 ± 13.97 | 54.82 ± 13.77 | 52.00 ± 14.71 | 0.40 |
Female, n (%) | 76 (79) | 56 (77) | 20 (87) | 0.39 |
Race, n (%) | 0.10 | |||
Black | 38 (40) | 31 (42) | 7 (30) | |
Ethnicity, n (%) (Hispanic) | 44 (54) | 35 (53) | 9 (56) | 0.82 |
Former or active smoke, n (%) | 41 (43) | 34 (47) | 7 (30) | 0.17 |
Pulmonary hypertension, n (%) | 28 (31) | 24 (33) | 4 (22) | 0.36 |
FVC predicted, n (%) | 0.37 | |||
Mild (> 76.9%) | 18 (22) | 17 (27) | 1 (5) | |
Moderate (64.3–76.8%) | 21 (25) | 15 (23) | 6 (32) | |
Severe (< 64.2%) | 44 (53) | 32 (50) | 12 (63) | |
DLCo predicted, n (%) | ||||
Normal | 11 (13) | 8 (13) | 3 (15) | |
Mild | 20 (24) | 14 (23) | 6 (30) | 0.30 |
Moderate | 26 (32) | 23 (37) | 3 (15) | |
Severe | 25 (30) | 17 (27) | 8 (40) | |
UIP ILD pattern, n (%) (2 missing) | 28 (30) | 23 (32) | 5 (23) | 0.41 |
NSIP ILD pattern, n (%) (2 missing) | 35 (37) | 26 (36) | 9 (41) | |
Immunosuppression, (n) % | 78 (81) | 59 (81) | 19 (83) | 1.00 |
Transplant referral, (n) % | 17 (18) | 17 (24) | 0 (0) | 0.01 |