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Table 1 Immunogenicity of Influenza H3N2 vaccine in juvenile systemic erythematosus (JSLE) patients and healthy controls

From: Safety and immunogenicity of influenza A(H3N2) component vaccine in juvenile systemic lupus erythematosus

 

JSLE

(n = 24)

Healthy controls (n = 29)

P

Before immunization

   

Seroprotection rate, n (%)

22 (91.7)

25 (86.2)

0.678

GMT, value (95% CI)

102.3

(75.0–139.4)

109.6

(68.2–176.2)

0.231

After immunization

   

Seroprotection rate, n (%)

24 (100)

28 (96.6)

1.000

Seroconversion rate, n (%)

4 (16.7)

9 (31.0)

0.338

GMT, value (95% CI)

162.3*

(132.9–198.3)

208.1*

(150.5–287.8)

0.143

Factor increase in GMT

1.6

(1.2–2.1)

1.9

(1.4–2.5)

0.574

  1. Results are expressed in median (95% CI) and n (%)
  2. GMT geometric mean titer
  3. *p < 0.001—comparison of GMT at D0 versus D30