Variable | Baseline | Year 1 | Year 2 | Year 3 | Year 4 | Year 5 | Year 6 | p |
---|---|---|---|---|---|---|---|---|
HAQ-DI median (25–75) | 1.625 b (1.031–2.094) n = 72 | 1.375 (0.625–2.0) n = 52 | 1.125 (0.594–1.875) n = 50 | 1.0 a (0.625–1.843) n = 48 | 1.125 (0.87–1.812) n = 49 | 1.25 (0.8 a 1.625) n = 43 | 1.187 (0.84–1.875) n = 30 | 0.015 |
DAPSA median (25–75) | 15.9 b (11.4–22.1) n = 57 | 12.8 (5.6–18.6) n = 47 | 10.9 (5.8–16.4) n = 50 | 13.8 (8.0–19.1) n = 45 | 11.6 a (7.1–17.1) n = 48 | 14.1 (8.3–19.9) n = 40 | 15.0 (9.4–22.1) n = 28 | 0.002 |
bDMARD use n (%) | 8 a (11,1%) n = 72 | 8 a (14,5%) n = 55 | 18 b (34%) n = 53 | 20 b (41,7%) n = 48 | 20 b (40%) n = 50 | 13 (31%) n = 42 | 9 (29%) n = 42 | < 0,001 |