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Table 2 Comparison of the frequency of the genotype and allele for rs10916199 and rs11588850 between the patients and the controls

From: Genetic polymorphism of WNT9A is functionally associated with thumb osteoarthritis in the Chinese population

rs10916199 (A/G)

Genotype

p

Allele

p

Odds ratio

(95% CI a)

AA

AG

GG

A

G

 

Patients

( n = 953)

699

(73.3%)

230 (24.1%)

24

(2.5%)

0.001

1628

(85.4%)

278

(14.6%)

0.001

0.73

(0.61–0.88)

 

Controls

( n = 1124)

890

(79.2%)

219 (19.5%)

15

(1.3%)

 

1999 (88.9%)

249

(11.1%)

  

rs11588850 (A/G)

Genotype

p

Allele

p

Odds ratio

(95% CI a)

AA

AG

GG

A

G

 

Patients

( n = 953)

714

(74.9%)

217 (22.8%)

22

(2.3%)

< 0.001

1643 (86.3%)

261

(13.7%)

< 0.001

0.66

(0.54–0.80)

 

Controls

( n = 1124)

920 (81.9%)

194 (17.2%)

10

(0.9%)

 

2034

(90.5%)

214

(9.5%)