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Fig. 1 | Advances in Rheumatology

Fig. 1

From: Genetic polymorphism of WNT9A is functionally associated with thumb osteoarthritis in the Chinese population

Fig. 1

Outcome of Luciferase reporter assay. The Luciferase reporter assays for rs11588850 (A/G) on WNT9A promoter were performed in the HEK293 cell lines. Empty pGL3-basic vector was used as reference. The WNT9A promoter can remarkably increase the expression of reporter vector as compared to the empty pGL3-basic vector (p < 0.05). The mutant allele G construct presented 29.1% higher enhancer activity than the wild allele A construct (p < 0.05)

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Advances in Rheumatology

ISSN: 2523-3106