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Table 4 The treatments and outcomes of IIM patients according to the levels of hs-cTnI.

From: The use of high-sensitivity cardiac troponin I in assessing cardiac involvement and Disease prognosis in idiopathic inflammatory myopathy

 

Total

(n = 142)

hs-cTnI < 30pg/mL

(n = 105)

hs-cTnI > 30pg/mL

(n = 37)

p - values

Treatments

Highest methyprednisolone dose (mg/day), median (IQR)

50.0 (40.0–80.0)

40.0 (20.0–80.0)

80.0 (80.0–80.0)

< 0.001

Application of MTX, n (%)

7 (4.9)

6 (5.7)

1 (2.7)

0.467

Application of CTX, n (%)

10 (7.0)

7 (6.7)

3 (8.1)

0.768

Application of IVIG, n (%)

23 (16.2)

14 (13.3)

9 (24.3)

0.119

Application of biologic agents, n (%)

6 (4.2)

1 (2.7)

5 (4.8)

0.592

Application of PE, n (%)

5 (3.5)

3 (2.9)

2 (5.4)

0.470

Application of beta blocker and ACE inhibitor/ARB, n (%)

18 (12.7)

8 (7.6)

10 (27.0)

0.002

Application of statin, n (%)

3 (2.1)

2 (1.9)

1 (2.7)

0.772

Application of antiplatelet/anticoagulant treatment, n (%)

14 (9.9)

4 (3.8)

10 (27.0)

< 0.001

Outcomes

Death, n (%)

3 (2.1)

0 (0.0)

3 (8.1)

0.004

  1. Values are presented as median with interquartile range for continuous variables, and as numbers with percentage for categorical variables. P < 0.05 is shown in bold type. ACE: angiotensin converting enzyme; ARB: angiotonin receptor blocker; CTX: Cyclophosphamide; IVIG, intravenous immunoglobulin; MTX, methotrexate; PE: plasma exchange