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Table 3 Logistic regression of risk factors for cardiac involvement in IIM patients

From: The use of high-sensitivity cardiac troponin I in assessing cardiac involvement and Disease prognosis in idiopathic inflammatory myopathy

 

univariate analysis

multivariate analysis

 

OR

95%CI

p-values

OR

95%CI

p-values

Age > 49.5 years

9.017

2.609–31.166

0.001

5.560

1.264–24.468

0.023

WBC > 11.4*10^9/L

3.982

1.793–8.843

0.001

2.247

0.747–6.755

0.149

CRP > 11.5 mg/L

3.763

1.658–8.538

0.002

1.307

0.332–5.155

0.702

ESR > 9.5 mm/h

2.756

1.300-5.841

0.008

1.680

0.492–5.741

0.408

CK-MB > 2.1 ng/mL

5.652

2.438–13.107

< 0.001

1.461

0.336–6.351

0.613

hs-cTnI > 13.8 pg/mL

16.706

6.695–41.686

< 0.001

7.810

1.962–31.097

0.004

Mb > 38.3 ng/mL

5.028

2.308–10.955

< 0.001

1.176

0.277–4.987

0.826

NT-proBNP > 247 pg/mL

11.144

4.792–25.915

< 0.001

2.858

0.889–9.188

0.078

LDH > 405 IU/L

3.867

1.724–8.671

0.001

0.245

0.049–1.211

0.084

AST > 49.5 IU/L

3.498

1.595–7.669

0.002

2.647

0.577–12.151

0.211

  1. ROC analyses were used to determine values at the maximum Youden index as cut-off points for continuous variables. Variables identified in the univariate logistic regression analysis (p < 0.05) were entered into a conditional forward multivariable logistic regression model to predict risk factors for cardiac involvement. P < 0.05 is shown in bold type. AST: aspartate aminotransferase; CI: confidence interval; CK-MB: creatine kinase MB; CRP: C-reactive protein; ESR: erythrocyte sedimentation rate; hs-cTnI: high-sensitivity cardiac troponin I; LDH: lactate dehydrogenase; Mb: myoglobin; NT-proBNP: N-terminal pro-B-type natriuretic peptide; OR: odds ratio; WBC: white blood cell