Comparative study of the synovial levels of RANKL and OPG in rheumatoid arthritis, spondyloarthritis and osteoarthritis

Table 3 Correlations of RANKL, OPG and RANKL/OPG with laboratory and radiographic parameters

		RANKL	OPG	RANKL/ OPG
Rheumatoid arthritis
CRP	r*	0.15	− 0.20	0.13
CRP	p	0.51	0.26	0.54
Cell count	r	0.59	− 0.08	0.55
Cell count	p	0.004	0.68	0.008
Bone erosions	r	− 0.22	0.12	− 0.40
Bone erosions	p	0.37	0.52	0.09
DAS28	r	0.30	0.28	0.21
DAS28	p	0.12	0.14	0.28
Spondyloarthritis
CRP	r	0.01	− 0.13	0.18
CRP	p	0.98	0.52	0.58
Cell count	r	− 0.11	0.22	− 0.09
Cell count	p	0.72	0.28	0.77
Bone erosions	r	0.30	− 0.19	0.20
Bone erosions	p	0.7	0.38	0.56
DAS28 or ASDAS-CRP	r	− 0.35	0.08	0.02
DAS28 or ASDAS-CRP	p	0.054	0.79	0.89
Osteoarthritis
CRP	r	0.41	− 0.41	0.82
CRP	p	0.28	0.17	0.006
Cell count	r	− 0.29	− 0.12	− 0.09
Cell count	p	0.48	0.71	0.83
Subchondral cysts or bone erosions	r	0.36	− 0.33	0.51
Subchondral cysts or bone erosions	p	0.25	0.20	0.09
Total
CRP	r	0.40	− 0.26	0.27
CRP	p	0.008	0.025	0.08
Subchondral cysts or bone erosions	r	0.05	− 0.09	0.04
Subchondral cysts or bone erosions	p	0.74	0.74	0.78

* Spearman’s correlation; CRP C-reactive protein; For statistical significance [bold], p < 0.05

ISSN: 2523-3106