Table 1 Top 10 up- and down-regulated DEmRNAs/DElncRNAs between patients with OA and normal controls
From: Screening crucial lncRNAs and genes in osteoarthritis by integrated analysis
Symbol | Combined ES | p-value | FDR | Regulation |
|---|---|---|---|---|
mRNA | ||||
TSPAN11 | 2.755519 | 0 | 0 | Up |
CFI | 2.462673 | 2.08E-13 | 7.46E-10 | Up |
SH3KBP1 | 2.213482 | 3.44E-13 | 1.03E-09 | Up |
GDE1 | 1.993256 | 5.58E-12 | 7.70E-09 | Up |
SPOCK1 | 2.152447 | 1.81E-11 | 2.03E-08 | Up |
SULF1 | 2.220866 | 2.67E-11 | 2.66E-08 | Up |
TNFAIP6 | 1.892005 | 6.03E-11 | 5.40E-08 | Up |
HOMER2 | 1.833474 | 6.63E-11 | 5.40E-08 | Up |
SERPINF1 | 2.677549 | 7.89E-11 | 6.15E-08 | Up |
AURKA | 1.803931 | 9.32E-11 | 6.69E-08 | Up |
MAFF | − 2.94493 | 0 | 0 | Down |
DDIT3 | − 2.9291 | 1.78E-15 | 1.06E-11 | Down |
ETS2 | − 2.4703 | 5.91E-14 | 2.65E-10 | Down |
MGEA5 | − 2.09142 | 7.62E-13 | 1.95E-09 | Down |
CEP95 | − 2.0568 | 2.80E-12 | 6.27E-09 | Down |
SLC38A3 | − 2.19521 | 4.12E-12 | 6.70E-09 | Down |
FNBP4 | − 2.1003 | 4.49E-12 | 6.70E-09 | Down |
STC2 | − 2.0997 | 4.46E-12 | 6.70E-09 | Down |
PIM3 | − 1.99638 | 3.73E-12 | 6.70E-09 | Down |
PRPF38A | − 1.95241 | 7.69E-12 | 9.85E-09 | Down |
lncRNA | ||||
RP11-754B17.1 | 0.465715266 | 1.43E-07 | 0.001295601 | Up |
RP1-45I4.3 | 0.466791971 | 3.11E-07 | 0.001295601 | Up |
RP11-159F24.3 | 0.246108899 | 4.63E-07 | 0.001295601 | Up |
LINC00412 | 0.394885033 | 4.79E-07 | 0.001295601 | Up |
RP11-131L23.2 | 0.467223628 | 5.71E-07 | 0.001295601 | Up |
RP11-293K20.3 | 0.646913761 | 5.93E-07 | 0.001295601 | Up |
RP11-474P2.7 | 0.381788287 | 8.15E-07 | 0.001556416 | Up |
RP11-370K11.1 | 0.301775904 | 9.39E-07 | 0.001586651 | Up |
RP11-381K20.2 | 0.221602241 | 1.06E-06 | 0.001586651 | Up |
LINC00377 | 0.235926968 | 1.32E-06 | 0.001686864 | Up |
AC093484.4 | − 0.525434637 | 3.85E-07 | 0.001295601 | Down |
RP11-383H13.1 | − 0.240895179 | 1.14E-06 | 0.001586651 | Down |
AP001434.2 | − 0.50423577 | 1.72E-06 | 0.00181637 | Down |
RP11-212E4.1 | − 0.734036745 | 1.90E-06 | 0.00181637 | Down |
RP11-229O3.1 | − 0.543410813 | 3.53E-06 | 0.002571151 | Down |
CRNDE | − 0.338423241 | 4.48E-06 | 0.002978185 | Down |
CTB-193M12.5 | − 0.307741547 | 6.89E-06 | 0.003514563 | Down |
CTD-2081C10.7 | − 0.393448166 | 6.89E-06 | 0.003514563 | Down |
RP11-752L20.3 | − 0.464335229 | 7.16E-06 | 0.003514563 | Down |
RP11-244F12.2 | − 0.538068417 | 9.01E-06 | 0.004050684 | Down |