Fig. 3

Electron microscopic analysis of fibroblast-like synoviocytes from patients with rheumatoid arthritis (A–C) and mice with collagen-induced arthritis (D–F). Both groups showed an abundant cytoplasm containing mitochondria (MT) with extensive rough endoplasmic reticulum (RER), with an euchromatic nucleus (N), mitochondria (MT), Golgi apparatus (GA), intermediate filaments (IF), lamellar bodies (LB) showing typical concentric walls, and pinocytotic vesicle (PV) in the cell membrane, showing the presence of pinocytosis (P). (4200-fold, 16,500-fold and 20,500-fold magnifications were used)