Table 4 Frequency of alterations in salivary gland histology in SLE patients with SS (SS+) and without SS (SS−)
Variable | Category | Total | SS | SS+ | p value |
|---|---|---|---|---|---|
n (%) | n (%) | n (%) | |||
Degree of inflammation (n = 105) | 0 | 29 (27.6) | 26 (39.4) | 3 (7.7) | < 0.001a |
1 | 32 (30.5) | 20 (30.3) | 12 (30.8) | ||
2 | 26 (24.8) | 18 (27.3) | 8 (20.5) | ||
3 | 4 (3.8) | 2 (3) | 2 (5.1) | ||
4 | 14 (13.3) | 0 (0) | 14 (35.9) | ||
Acinar atrophy (n = 102) | Absent | 44 (43.1) | 29 (46) | 15 (38.4) | 0.129a |
Discreet | 50 (49) | 31 (49.2) | 19 (48.7) | ||
Focal | 1 (1) | 0 (0) | 1 (2.6) | ||
Moderate | 7 (6.9) | 3 (4.8) | 4 (10.3) | ||
Ductal dilatation (n = 102) | Absent | 29 (28.4) | 17 (27) | 12 (30.8) | 0.052 |
Discreet | 64 (62.7) | 43 (68.3) | 21 (53.8) | ||
Moderate | 9 (8.8) | 3 (4.8) | 6 (15.4) | ||
Adipose infiltration (n = 102) | Absent | 45 (44.1) | 27 (42.9) | 18 (46.1) | 0.088 |
Discreet | 47 (46.1) | 32 (50.8) | 15 (38.5) | ||
Moderate | 10 (9.8) | 4 (6.3) | 6 (15.4) | ||
Germinal center (n = 95) | Absent | 94 (98.9) | 63 (100) | 31 (96.9) | 0.359a |
Present | 1 (1.1) | 0 (0) | 1 (3.1) | ||
LE infiltrate (n = 93) | Absent | 89 (95.7) | 57 (98.3) | 32 (91.4) | 0.127a |
Present | 4 (4.3) | 1 (1.7) | 3 (8.6) |