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Fig. 4 | Advances in Rheumatology

Fig. 4

From: Fasciola hepatica extract suppresses fibroblast-like synoviocytes in vitro and alleviates experimental arthritis

Fig. 4

F. hepatica extract reduced the adherence efficiency, the migratory, and invasion potentials of FLS. A Adherence capacity of FLS was analyzed after 6 h of F. hepatica extract incubation (100 µg/mL) (n = 4). B Migratory potential of FLS after wound healing (n = 3). C Representative microscopy images of FLS migration assay. D Invasive capacity of FLS was evaluated by matrigel assay (n = 3). E Representative images of stained cells that invaded through matrigel invasion chambers. F TNF-α secretion by FLS after INF-© stimulation (n = 3) G IL-6 secretion by FLS after INF-γ stimulation (n = 3). Original magnification: 20×. T Test; Data are expressed as mean ± SD; p < 0.05

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