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Table 4 ROC curves of the three markers for the independent and combined diagnosis of ILD

From: Serum MMP-9, SP-D, and VEGF levels reflect the severity of connective tissue disease-associated interstitial lung diseases

Biomarker

AUC of ROC

95% CI

Sensitivity %

Specificity %

Cut-off valve

MMP-9

0.867

0.784

0.950

81.8

81.8

326.80 ng/ml

SP-D

0.801

0.710

0.892

90.9

40.0

68.88 ng/ml

VEGF

0.905

0.842

0.968

87.9

83.6

277.60 pg/ml

Combine

0.952

0.912

0.992

96.0

78.7

–

  1. AUC area under the curve, ROC receiver operating characteristic curve, CI confidence interval
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Advances in Rheumatology

ISSN: 2523-3106