Table 2 Tuberculosis screening tests, treatment, and risk factors for tuberculosis in Portuguese and Brazilian juvenile idiopathic arthritis populations
Portuguese | Brazilian | p value | Total | |
|---|---|---|---|---|
Number of patients (%) | 188 (64.4) | 104 (35.6) | – | 292 (100) |
Reason for screening (%) | < 0.001 | |||
At disease onset | 55 (29.3) | 63 (60.6) | 118 (0.4) | |
Before treatment | 127 (67.7) | 36 (34.6) | 163 (5.8) | |
Other*1 | 6 (3.2) | 5 (4.8) | 11 (3.8) | |
Age at screening | ||||
At JIA onset | 8.9 ± 5.4 | 7.2 ± 4.2 | 0.064 | ± 4.9 |
At treatment start | ||||
Before bDMARDs (years of age) | 11.9 ± 5.8 | 9.5 ± 2.8 | 0.162 | 11.5 ± 5.6 |
Number (%) | 72 (38.3) | 15 (14.4) | < 0.001 | 87 (29.8) |
Before cDMARDs (years of age) | 9.6 ± 5.1 | 9.2 ± 3.7 | 0.692 | 9.5 ± 4.7 |
Number (%) | 55 (29.3) | 21 (20.2) | 0.091 | 76 (26) |
Other*1 | 18.5 ± 2.1 | 5.4 ± 3.5 | < 0.001 | 11.2 ± 7.4 |
TST performed as single test (%) | 92 (48.9) | 102 (98.1) | < 0.001 | 194 (66.4) |
TST ≥ 5 mm (%) | 8 (8.7) | 11 (10.8) | 0.625 | 19 (9.8) |
IGRA performed as single test (%) | 13 (6.9) | 1 (1) | 0.023 | 14 (4.8) |
IGRA positive (%) | 0 (0) | 1 (100) | 0.071 | 1 (7.1) |
TST and IGRA performed (%) | 83 (44.1) | 1 (1) | < 0.001 | 84 (28.8) |
TST ≥ 5 mm (%) | 10 (12) | 0 | 0.999 | 10 (11.9) |
IGRA positive (%) | 3 (3.6) | 0 | 0.999 | 3 (3.6) |
TST and IGRA positive (%) | 0 | 0 | – | 0 |
LTBI therapy (Isoniazid) (%) | 20 (10.6) | 11 (10.6) | 0.999 | 31 (10.6) |
Chest X-ray performed (%) | 145 (77.1) | 58 (55.8) | < 0.001 | 203 (69.5) |
Abnormal chest X-ray (%)*2 | 4 (2.8) | 4 (6.9) | 0.171 | 8 (3.9) |
Immigrant from highrisk countries (%) | 3 (1.6) | 1 (1) | 0.547 | 4 (1.4) |
Exposure by contact TB cases (%) | 3 (1.6) | 3 (2.9) | 0.592 | 6 (2.1) |
Tuberculosis treatment (%) | 1 (0.5) | 2 (1.9) | 0.290 | 3 (1) |
Background of low socio-educational level | 37 (19.7) | 21 (20.2) | 0.916 | 58 (19.9) |