Skip to main content

Table 3 Post-intervention values of estimated effects for all outcomes evaluated

From: The impact of a low-calorie, low-glycemic diet on systemic lupus erythematosus: a systematic review

Outcome

Studies

N

MD

Lower 95%

Higher 95%

Diet effects compared to control

     

Quality of life

     

6 weeks

1

16

16.30

5.91

26.69

12 weeks

1

16

14.60

0.88

28.32

Lipid profile – 6 weeks

     

HDL

1

16

5.50

− 7.21

18.21

LDL

1

16

5.70

16.72

28.12

Triglyceride

1

16

− 2.50

− 70.67

65.67

Lipid profile – 12 weeks

     

HDL

1

16

3.90

17.54

9.74

LDL

1

16

15.30

− 8.12

38.72

Triglyceride

1

16

− 13.40

− 50.27

23.47

Lipid profile – 9 months

     

HDL

1

31

4.30

− 6.96

15.56

LDL

1

31

− 13.15

− 29.38

3.08

Triglyceride

1

31

11.30

− 16.90

39.50

   

RR

Lower 95%

Higher 95%

Disease activity (SLEDAI 2 K > 4) – 6 weeks

1

31

1.07

0.32

3.52

Outcome

Studies

N

MD

Lower 95%

Higher 95%

Comparison between the low glycemic index diet and the calorie-restricted diet

     

Fatigue, quality of sleep, disease activity – 6 weeks

     

Fatigue Severity Scale

1

23

0.00

− 1.20

1.20

Pittsburgh Sleep/Quality Index

1

23

0.50

− 3.14

4.14

British Isles Lupus Assessment Group

1

23

0.00

− 3.52

3.52

European Consensus Lupus Activity Measurement

1

23

− 0.90

− 1.94

0.14

Lipid profile – 6 weeks

     

HDL

1

23

− 0.24

− 0.48

− 0.00

LDL

1

23

− 1.00

− 1.60

− 0.40

Triglyceride

1

23

− 0.35

− 0.89

0.19

  1. MD = mean difference; RR = relative risk; HDL = high-density lipoprotein; LDL = low-density lipoprotein; SLEDAI = Systemic Lupus Erythematosus Disease Activity Index