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Table 3 Correlation between YKL-40 serum levels and continuous variables (demographic, clinical, laboratory and lung parameters, and disease status) of the patients with antisynthetase syndrome

From: High YKL-40 serum levels and its expression in the muscle tissues of patients with antisynthetase syndrome

  rho P
Demographic data
 Age 0.294 0.040
Clinical parameters
 Fever 0.070 0.631
 Raynaud phenomenon 0.144 0.324
 “Mechanic’s hands” −0.045 0.757
 Muscle involvement −0.219 0.131
 Joint involvement −0.190 0.192
Laboratory parameters
 TNF-α level 0.382 0.007
 IFN-γ level 0.125 0.395
Lung involvement
 FVC (% predict) 0.018 0.930
 FEV1 (% predicted) 0.089 0.667
 FEV1/FVC ratio −0.066 0.758
 DLCO2 (% predicted) 0.533 0.091
Disease status
 MMT-8 0.037 0.801
 Patient’ VAS −0.173 0.239
 Physician’ VAS −0.234 0.110
 MYOACT −0.077 0.614
 HAQ 0.166 0.266
 Creatine phosphokinase 0.131 0.371
 Lactate dehydrogenase 0.138 0.460
 Aspartate aminotransferase 0.033 0.854
 Alanine aminotransferase 0.034 0.866
Treatment
 Prednisone: dose (mg/day) 0.217 0.139
  1. DLCO2 diffusion of carbon dioxide; FEV1 forced expiratory volume in one second; FVC forced vital capacity; HAQ Health Assessment Questionnaire; IFN interferon; MMT-8 Manual Muscle Testing; MYOACT Myositis Disease Activity Assessment Visual Analogue Scales; TNF tumor necrosis factor; VAS Visual Analog Scale