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Table 2 Comparison of the quantitative variables according to the BDNF Val66Met genotypes

From: The genetic influence of the brain-derived neurotrophic factor Val66Met polymorphism in chronic low back pain

Variable

Val/ Val (n = 81)

Val/Met (n = 26)

P-value

Age

46.2 ± 14.3

46.5 ± 14.6

0.73

Subjective assessment of stress

5.9 ± 2.5

5.8 ± 2.1

0.62

BMI

27.1 ± 5.2

26.4 ± 4.9

0.47

Total CSI score

50.3 ± 14.6

48.0 ± 13.9

0.50

Total RMDQ score

15.6 ± 5.5

15.8 ± 4.8

0.99

BIP pain intensity

 Worst

6.5 ± 2.5

6.4 ± 2.9

0.97

 Least

3.2 ± 2.4

2.8 ± 2.4

0.42

 Average

5.4 ± 2.1

5.2 ± 2.8

0.52

 Now

4.6 ± 3.0

4.2 ± 3.0

0.45

BIP interference

 General activity

5.9 ± 3.4

5.4 ± 3.2

0.44

 Mood

5.7 ± 3.5

4.9 ± 3.7

0.36

 Walking

5.4 ± 3.2

5.3 ± 3.5

0.96

 Normal work

6.1 ± 3.8

5.3 ± 3.4

0.16

 Relation

3.6 ± 3.4

3.5 ± 3.2

0.92

 Sleep

5.4 ± 3.6

5.3 ± 3.2

0.76

 Enjoyment of life

4.3 ± 3.7

5.1 ± 3.5

0.34

Summation of pain body regions

9.0 ± 5.0

8.7 ± 8.8

0.07

Total Tampa score

45.6 ± 8.1

45.9 ± 7.2

0.87

Total PCS score

2.2 ± 1.2

1.9 ± 1.1

0.32

 PCS rumination

2.8 ± 1.4

2.3 ± 1.1

0.18

 PCS helplessness

1.5 ± 1.3

1.4 ± 1.4

0.51

HADS anxiety

9.3 ± 3.5

8.4 ± 3.5

0.52

HADS depression

7.1 ± 3.8

6.6 ± 4.4

0.35

  1. Values are shown as mean ± standard deviation
  2. BMI body mass index, BPI the brief inventory of pain, CSI central sensitization inventory, HADS hospital anxiety and depression scale, PCS pain catastrophizing scale, RMDQ Rolland-Morris disability questionnaire
  3. P-value for the Mann-Whitney test