Fig. 1

Frequency and severity of adverse drug reaction. Frequency and severity of ADRs of medication used in patients with JIA, JSLE, and JDM. The vertical axis shows the percentage of adverse drug reactions of each medication. The horizontal axis shows the degree of severity of adverse drug reaction. ADR – adverse drug reaction. JIA – juvenile idiopathic arthritis. JSLE – juvenile systemic lupus erythematosus. JDM – juvenile dermatomyositis. LT – life threatening adverse event; S – severe adverse drug reaction; M – mild adverse drug reaction; MOD – moderate adverse drug reaction. % - percentage. ADA – adalimumab. AZA – azathioprine. CPA – cyclophosphamide. GCs – glucocorticoids. CSA – cyclosporine. CQ – diphosphate chloroquine. ETN – etanercept. HCQ – hydroxychloroquine. IFX – infliximab. IVIG – intravenous immunoglobulin. LEF – leflunomide. MMF – mycophenolate mofetil. MTX – methotrexate. RTX – rituximab. TCZ – tocilizumab