Table 3 Active HHV infection detected via Nested-PCR in the DNA extracted from the serum samples
Patient | Age (years) | HHV-DNA | SLEDAI | Clinical symptoms in case of positive HHV-DNA | DI | Drug |
|---|---|---|---|---|---|---|
MJBS | 20 | HCMV+HHV-7 | 12 | CNS vasculitis, leukocyturia, headache, weakness, urinary tract infection. | 3 | Pred+Mtx |
SRGS | 45 | HCMV | 12 | Hospitalization. Edema, fever, vomiting and diarrhea, HCMV disease in GIT; ganciclovir treatment. | 3 | Pred+CP + Aza |
MPM | 34 | HSV-1 | 12 | Abdominal pains and heart cramps when in the ventral decubitus position and bilateral paresthesia. | 2 | Pred |
NDRS | 43 | HCMV | 11 | Hospitalization for UTI (antibiotic) and disseminated SLE. | 2 | Pred+CFF |
LRMa | 31 | HCMV | 10 | Hospitalization died of pulmonary HCMV. Leucopenia, acute respiratory failure, sepsis and multiple organs failure, generalized edema, tachypnea, fever, anemia, high HSV, low C3 and C4, proteinuria, hematuria | 3 | Metpred, Pred, CP, Pred.100 mg |
MMS | 27 | HHV-7 | 10 | Hospitalization. Died of sepsis and refractory shock. Pseudomonas aeruginosa, skin with SLE, weakness, drowsiness, joint pain, and little urination with generalized edema, arthralgia in hands, shoulder, hips, knees and ankles | 3 | Aza |
MFO | 48 | HHV-7 | 10 | Arthralgia, headache | 1 | Pred |
AMSA | 33 | HSV-2 | 9 | Convulsion for more than 8 days. Severe headache and persistent joint pain in the lower limbs. | 3 | Pred |
MPP | 24 | HCMV | 8 | Proteinuria, hypertension, obesity | 3 | Pred+Aza |
LSR | 41 | HHV1 + HHV-7 | 8 | Proteinuria, Candida albicans onychomycosis, multipolar dermatofibroma, psoriasis versicolor | 3 | Metilpred |
SM | 33 | HHV-7 | 8 | Headache, photosensitivity | 3 | Aza |
FDO | 34 | HCMV+ HHV-7 | 4 | Articular pains in the hands, lumbar spine with edema; pain in the sacral region when moving | 3 | Mtx |
MASP | 47 | HSV-1 | 1 | Joint pain mainly in the hands, limb femoral arthralgia, asthma and idiopathic thrombocytopenic purpura | 3 | Pred |
MAB | 46 | HSV-1 | 0 | Arthritis, photosensitivity, autoimmune hepatitis, neutrophilic cutaneous vasculitis, esophageal varices, aseptic leukocyturia | 3 | Pred/Aza |
CMT | 23 | HSV-1 | 0 | Intermittent joint and lumbar pain, cough with mucoid expectoration | 3 | Pred/Aza |