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Table 2 − Allele and genotype frequencies of the Val66Met variant (n = 216)

From: Pain catastrophizing is associated with the Val66Met polymorphism of the brain-derived neurotrophic factor in fibromyalgia

 

FM

Controls

P

(n = 108)

(n = 108)

 

Allele

  

0.045

 Val (G)

195 (90.3)

181 (83.8)

 

 Met (A)

21 (9.7)

35 (16.2)

 

Genotype model

  

0.069

 Val/Val

87 (80.6)

77 (71.3)

 

 Val/Met

21 (19.4)

27 (25.0)

 

 Met/Met

–

4 (3.7)

 

Met dominant modela

  

0.111

 Val/Met + Met/Met

21 (19.4)

31 (28.7)

 

 Val//Val

87 (80.6)

77 (71.3)

 
  1. Notes. Data are presented as frequency and percentage (% in parentheses). P values refer to comparison between FM allele and genotype frequencies and controls and are based on Chi-square tests
  2. a Met dominant model: OR = 1,67; 95% CI = 0.85–3.32
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Advances in Rheumatology

ISSN: 2523-3106