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Table 2 − Allele and genotype frequencies of the Val66Met variant (n = 216)

From: Pain catastrophizing is associated with the Val66Met polymorphism of the brain-derived neurotrophic factor in fibromyalgia

  FM Controls P
(n = 108) (n = 108)  
Allele    0.045
 Val (G) 195 (90.3) 181 (83.8)  
 Met (A) 21 (9.7) 35 (16.2)  
Genotype model    0.069
 Val/Val 87 (80.6) 77 (71.3)  
 Val/Met 21 (19.4) 27 (25.0)  
 Met/Met 4 (3.7)  
Met dominant modela    0.111
 Val/Met + Met/Met 21 (19.4) 31 (28.7)  
 Val//Val 87 (80.6) 77 (71.3)  
  1. Notes. Data are presented as frequency and percentage (% in parentheses). P values refer to comparison between FM allele and genotype frequencies and controls and are based on Chi-square tests
  2. a Met dominant model: OR = 1,67; 95% CI = 0.85–3.32