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Table 3 Comparison of objective pain measures and oxidative stress markers between FMS Sham-rTMS and Real-rTMS group

From: Repetitive transcranial magnetic stimulation of the prefrontal cortex for fibromyalgia syndrome: a randomised controlled trial with 6-months follow up

 

Pre-rTMS

Post-rTMS

Follow-up

FU-1 (15-days)

NFR: Latency (ms)

 Sham

105.0 (95.0–124.4)

105.0 (90.0–120.0)

102.0 (87.6–104.0)

 Real

110.0 (95.5–137.8)

106.5 (97.6–120.8)

105.0 (97.3–120.0)

 p*

0.41

0.06

0.05

NFR: Duration (ms)

 Sham

42.5 (40.0–47.5)

42.5 (40.0–45.5)

45.0 (40.0–50.0)

 Real

40.5 (38.3–45.25)

40.0 (38.65–45.0)

42.3 (40.0–45.0)

 p*

0.52

0.06

0.07

NFR: Amplitude ((μV)

 Sham

294.0 (273.0–312.0)

287.0 (263.3–297.0)

284.5 (260.8–298.5)

 Real

281.6 (260.5 ± 314.3)

276.0 (234.5–311.5)

276.0 (243.8–295.2)

 p*

0.42

0.28

0.35

DNIC: Threshold (V)

 Sham

21.0 (18.5–24.5)

21.0 (20.0–24.0)

22.0 (19.0–25.0)

 Real

22.0 (18.0–25.5)

27.0 (25.0–34.0) ##

29.0 (25.0–39.0)

 p*

0.75

0.001

0.001

Thiobarbituric acid reactive substances; TBARS (ng/ml)

 Sham

0.88 (0.11–2.3)

0.90 (0.22–2.11)

 Real

0.97 (0.23–2.1)

0.78 (0.18–1.6)

 p*

0.71

0.07

F2-isoprostanes (pg/ml)

 Sham

209.8 (135.8–317.4)

183.9 (123.6–251.4)

 Real

180.4 (78.35–243.8)

181.9 (89.4–315.3)

 p*

0.14

0.19

  1. Sham (n = 41) and Real (n = 45); Data is presented as Median (25Q-75Q); NFR: Nociceptive flexion reflex. Asterisk (*) symbol indicates p value between Sham-rTMS and Real-rTMS group. Hash (#) symbol indicates p value within group. Hyphen-minus (−) symbol indicates that the data not recorded. *p or #p < 0.05; **p or ##p < 0.01; ***p or ###p < 0.001