Fig. 2

Proposed mechanisms of action of antimalarials (chloroquine and hydroxychloroquine). APL: antiphospholipids; CQ: chloroquine; HCQ: hydroxychloroquine; IL-1: interleukin 1; IL-6: interleukin-6; INF-α: interferon alpha; INF-γ: interferon gama; PLA-2: phospholipase A-2; TCR: T cell receptor; TLR: toll like receptor; TNF: tumor necrose factor