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Table 3 Rheumatic manifestations in Fabry disease patients

From: Higher rate of rheumatic manifestations and delay in diagnosis in Brazilian Fabry disease patients

Signs/Symptoms/DiagnosisTotal
N (%)
Males
N (%)
Females
N (%)
p-value
Pain in the extremities (nociceptive and/or neuropathic)26 (70.3%)13 (81.3%)13 (61.9%)0.21
Fabry crises (past/present)15 (40.5%)10 (62.5%)5 (23.8%)0.02
Osteopenia/osteoporosis/ low bone mineral density for age24 (64.8%)13 (81.3%)11 (52.4%)0.07
Fibromyalgia16 (43.2%)6 (37.5%)10 (47.6%)0.55
Lymphedema8 (21.6%)7 (43.8%)1 (4.8%)0.003
Neuropathic osteoarthropathy (Charcot foot) (2 patients = toe amputation)4 (10.8%)3 (18.8%)1 (4.8%)0.18
Chronic low back pain5 (13.5%)1 (6.3%)4 (19%)0.27
Hip/knee osteoarthritis5 (13.5%)3 (18.8%)2 (9.5%)0.43
Gout1 (2.7%)01 (4.8%)
Clinodactyly1 (2.7%)1 (6.3%)0
HyperCKemia1 (2.7%)1 (6.3%)0
Carpal tunnel syndrome3 (8.1%)03 (14.3%)0.12
  1. Data in bold means that the difference of frequencies between males and females was statistically significant