Skip to main content

Table 2 Relationship between the genotype and allele distributions of the TNF –G308A and the severity of knee and hip osteoarthritis according to the degree of radiological impairment

From: Functional status and severity of osteoarthritis in elderly is associated to the polymorphism of TNFA gene

  Radiological Impairment
Mild Moderate/Severe
Hip
Genotype Frequency
 GG 19 (65.5%) 05 (41.7%)
 GA 08 (27.6%) 03 (25.0%)
 AA 02 (6.9%) 04 (33.3%)
 Total 29 (100.0%) 12 (100.0%)
Allele Frequency*
 G 46 (79.3%) 13 (54.2%)
 A 12 (21.7%) 11 (45.8%)
 Total 58 (100.0%) 24 (100.0%)
Knee
 GG 14 (73.7%) 11 (34.4%)
 GA 02 (10.5%) 14 (43.7%)
 AA 03 (15.8%) 07 (21.9%)
 Total 19 (100.0%) 32 (100.0%)
Allele Frequency*
 G 30 (78.9%) 36 (56.2%)
 A 08 (21.1%) 28 (43.8%)
 Total 38 (100.0%) 64 (100.0%)
  1. *Statistically significant, χ2 test, p < 0.05