Table 2 Relationship between the genotype and allele distributions of the TNF –G308A and the severity of knee and hip osteoarthritis according to the degree of radiological impairment
Radiological Impairment | ||
|---|---|---|
Mild | Moderate/Severe | |
Hip | ||
Genotype Frequency | ||
GG | 19 (65.5%) | 05 (41.7%) |
GA | 08 (27.6%) | 03 (25.0%) |
AA | 02 (6.9%) | 04 (33.3%) |
Total | 29 (100.0%) | 12 (100.0%) |
Allele Frequency* | ||
G | 46 (79.3%) | 13 (54.2%) |
A | 12 (21.7%) | 11 (45.8%) |
Total | 58 (100.0%) | 24 (100.0%) |
Knee | ||
GG | 14 (73.7%) | 11 (34.4%) |
GA | 02 (10.5%) | 14 (43.7%) |
AA | 03 (15.8%) | 07 (21.9%) |
Total | 19 (100.0%) | 32 (100.0%) |
Allele Frequency* | ||
G | 30 (78.9%) | 36 (56.2%) |
A | 08 (21.1%) | 28 (43.8%) |
Total | 38 (100.0%) | 64 (100.0%) |