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Table 1 Demographic and clinical features of the SSc patients

From: Risk of digital ulcers occurrence in systemic sclerosis: a cross-sectional study

Variable Patients with SSc (n 70)
Age (years), mean ± SD 46.78 ± 12.52
Gender (F/M), (%) 65/5 (92.9/7.1)
RP duration (years), mean ± SD 5.10 ± 6.15
Disease duration (years), mean ± SD 9.41 ± 6.26
Cutaneous subset (Diffuse/Limited), n (%) 25/45 (35.7/64.3)
Modified Rodnan cutaneous score, mean ± SD 13.11 ± 10.55
Clinical manifestations
 Calcinosis, n (%) 11 (15.7)
 Puffy fingers, (%) 13 (18.6)
 Digital pitting scars, n (%) 28 (40.0)
 Active digital ulcers, n (%) 14 (20.0)
 Necrosis or amputation of extremities, n (%) 4 (5.7)
 Telangiectasia, n (%) 38 (54.3)
 Arthritis, n (%) 20 (28.6)
 Hand flexion contracture, n (%) 10 (14.3)
 Tendon friction rubs, n (%) 4 (5.7)
 Esophageal involvement, n (%) 53 (75.7)
 FVC < 70% predicted, n (%) 19 (27.1)
 Interstitial lung involvement on CT scan, n (%) 34 (48.6)
 PAH, n (%) 7 (10.0)
 Diastolic dysfunction, n (%) 17 (24.3)
 Renal crisis, n (%) 3 (4.3)
Antibodies and serum markers
 ACA, n (%) 28 (40.0)
 Anti-Scl-70, n (%) 21 (30.0)
 Anti-RNA polymerase III, n (%) 5 (7.1)
 IgG anti-annexin V, n (%) 11 (15.7)
 IgM anti-annexin V, n (%) 10 (14.3)
 Endothelin-1 (pg/ml) 2.04 ± 1.49
 ESR (mmHg) 30.50 ± 19.09
 C-reactive protein (mg/L) 8.81 ± 8.97
Summed Medsger Disease Severity Scale (MDSS) score (range 0–10) 5.91 ± 3.09
Raynaud Condition Score (RCS) (range 0–10) 5.29 ± 2.27
Duration of RP attacks (minutes) 23.54 ± 19.80
Number of RP attacks 2.87 ± 1.84
HAQ-DI (range 0–3) 0.77 ± 0.05
SHAQ VAS for RP 5.26 ± 2.25
SHAQ VAS for digital ulcers 3.41 ± 2.30
  1. Results are presented as mean ± standard deviation or absolute frequency (relative frequency)
  2. RP: Raynaud’s phenomenon; FVC: forced vital capacity; CT: computed tomography; PAH: pulmonary arterial hypertension; ACA: anticentromere; ESR: erythrocyte sedimentation rate; HAQ-DI: Health assessment questionnaire disability index; SHAQ: Scleroderma Health assessment questionnaire; VAS: analogic visual scale