Table 1 Demographic and clinical features of the SSc patients
From: Risk of digital ulcers occurrence in systemic sclerosis: a cross-sectional study
Variable | Patients with SSc (n 70) |
|---|---|
Age (years), mean ± SD | 46.78 ± 12.52 |
Gender (F/M), (%) | 65/5 (92.9/7.1) |
RP duration (years), mean ± SD | 5.10 ± 6.15 |
Disease duration (years), mean ± SD | 9.41 ± 6.26 |
Cutaneous subset (Diffuse/Limited), n (%) | 25/45 (35.7/64.3) |
Modified Rodnan cutaneous score, mean ± SD | 13.11 ± 10.55 |
Clinical manifestations | |
Calcinosis, n (%) | 11 (15.7) |
Puffy fingers, (%) | 13 (18.6) |
Digital pitting scars, n (%) | 28 (40.0) |
Active digital ulcers, n (%) | 14 (20.0) |
Necrosis or amputation of extremities, n (%) | 4 (5.7) |
Telangiectasia, n (%) | 38 (54.3) |
Arthritis, n (%) | 20 (28.6) |
Hand flexion contracture, n (%) | 10 (14.3) |
Tendon friction rubs, n (%) | 4 (5.7) |
Esophageal involvement, n (%) | 53 (75.7) |
FVC < 70% predicted, n (%) | 19 (27.1) |
Interstitial lung involvement on CT scan, n (%) | 34 (48.6) |
PAH, n (%) | 7 (10.0) |
Diastolic dysfunction, n (%) | 17 (24.3) |
Renal crisis, n (%) | 3 (4.3) |
Antibodies and serum markers | |
ACA, n (%) | 28 (40.0) |
Anti-Scl-70, n (%) | 21 (30.0) |
Anti-RNA polymerase III, n (%) | 5 (7.1) |
IgG anti-annexin V, n (%) | 11 (15.7) |
IgM anti-annexin V, n (%) | 10 (14.3) |
Endothelin-1 (pg/ml) | 2.04 ± 1.49 |
ESR (mmHg) | 30.50 ± 19.09 |
C-reactive protein (mg/L) | 8.81 ± 8.97 |
Summed Medsger Disease Severity Scale (MDSS) score (range 0–10) | 5.91 ± 3.09 |
Raynaud Condition Score (RCS) (range 0–10) | 5.29 ± 2.27 |
Duration of RP attacks (minutes) | 23.54 ± 19.80 |
Number of RP attacks | 2.87 ± 1.84 |
HAQ-DI (range 0–3) | 0.77 ± 0.05 |
SHAQ VAS for RP | 5.26 ± 2.25 |
SHAQ VAS for digital ulcers | 3.41 ± 2.30 |