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  2. Sickle cell disease (SCD) is an autosomal recessive genetic disease in which a mutation occurs in the β-globin chain gene, resulting in abnormal hemoglobin levels. In an environment with reduced oxygen concent...

    Authors: Taciana Fernandes Araújo Ferreira, Ana Paula Teixeira dos Santos, Alexandra Silva Leal, Gilberto de Araújo Pereira, Sheila Soares Silva and Helio Moraes-Souza
    Citation: Advances in Rheumatology 2021 61:11
    Content type: Research Published on:

  3. Fibromyalgia is a chronic pain disorder characterized by widespread musculoskeletal symptoms, primarily attributed to sensitization of somatosensory system carrying pain. Few reports have investigated the impa...

    Authors: Vikas Kumar Tiwari, Srishti Nanda, Suvercha Arya, Uma Kumar, Ratna Sharma, Senthil S. Kumaran and Renu Bhatia
    Citation: Advances in Rheumatology 2021 61:10
    Content type: Research Published on:

  4. In the past 20 years, hematopoietic stem cell transplantation (HSCT) has been investigated as treatment for systemic sclerosis (SSc). The goal of HSCT is to eradicate the autoreactive immune system, which is r...

    Authors: Álvaro Henrique-Neto, Marianna Yumi Kawashima Vasconcelos, Juliana Bernardes Elias Dias, Daniela Aparecida de Moraes, Maynara Santana Gonçalves, Djúlio César Zanin-Silva, Talita Graminha Zucoloto, Marília de Fátima Cirioli de Oliveira, Giuliana Martinelli Dotoli, Luiz Fernando Weffort, Vanessa Cristina Leopoldo and Maria Carolina Oliveira
    Citation: Advances in Rheumatology 2021 61:9
    Content type: Research Published on:

  5. Sjögren’s Syndrome compromises the exocrine function, producing xerostomia and xerophthalmia. It can appear as an isolated condition or associated with other autoimmune diseases (polyautoimmunity). The Unstimu...

    Authors: María Alejandra Martínez-Ceballos, Natalia Aguilera, Kenny Carolina Garzón-González, Jairo Cajamarca-Baron, Juan Pablo Alzate-Granados and Adriana Rojas-Villarraga
    Citation: Advances in Rheumatology 2021 61:8
    Content type: Research Published on:

  6. To compare the efficacy and safety of a new formulation of a fixed dose combination of glucosamine sulfate (GS; 1500 mg) and bovine chondroitin sulfate (CS; 1200 mg) versus the reference product (RP) in patien...

    Authors: Andrea Barranjard Vannucci Lomonte, Emerson Gimenez, Antônio Carlos da Silva, Sebastião Cezar Radominski, Morton Aaron Scheinberg, Antônio Carlos Ximenes and Cristiano Augusto de Freitas Zerbini
    Citation: Advances in Rheumatology 2021 61:7
    Content type: Research Published on:

  7. Complementary and alternative medicine (CAM) use is prevalent among patients living with arthritis. Such patients often seek information online, for the purpose of gaining a second opinion to their healthcare ...

    Authors: Jeremy Y. Ng, Alexandra Vacca and Tanya Jain
    Citation: Advances in Rheumatology 2021 61:6
    Content type: Research Published on:

  8. Abdominal symptoms in patients with primary Sjögren syndrome (pSS) are poorly documented. The objective of the study was to describe the abdominal symptoms of patients with pSS and to assess their association ...

    Authors: Simon Parreau, Jérémie Jacques, Stéphanie Dumonteil, Sylvain. Palat, Sophie Geyl, Guillaume Gondran, Holy Bezanahary, Eric Liozon, Julie Azaïs, Stéphanie Colombie, Marie-Odile Jauberteau, Véronique Loustaud-Ratti, Kim-Heang Ly and Anne-Laure Fauchais
    Citation: Advances in Rheumatology 2021 61:5
    Content type: Research Published on:

  9. Spondyloarthritis (SpA) is a group of chronic inflammatory systemic diseases characterized by axial and/or peripheral joints inflammation, as well as extra-articular manifestations. Over some decades, nonstero...

    Authors: Ricardo da Cruz Lage, Claudia Diniz Lopes Marques, Thauana Luiza Oliveira, Gustavo Gomes Resende, Charles Lubianca Kohem, Carla Gonçalves Saad, Antônio Carlos Ximenes, Célio Roberto Gonçalves, Washington Alves Bianchi, Eduardo de Souza Meirelles, Mauro Waldemar Keiserman, Adriano Chiereghin, Cristiano Barbosa Campanholo, André Marun Lyrio, Cláudia Goldenstein Schainberg, Lenise Brandao Pieruccetti…
    Citation: Advances in Rheumatology 2021 61:4
    Content type: Position article and guidelines Published on:

  10. Whole-body cryotherapy (WBC) has shown to be beneficial in the treatment of fibromyalgia (FM). There is cumulative evidence that cytokines play a crucial role in FM. It’s unknown whether clinical effects of WB...

    Authors: Philipp Klemm, Johanna Becker, Iris Aykara, Thomas Asendorf, Gabriel Dischereit, Elena Neumann, Ulf Müller-Ladner and Uwe Lange
    Citation: Advances in Rheumatology 2021 61:3
    Content type: Research Published on:

  11. Large epidemiologic and clinical estimates of spondyloarthritis (SpA) in Latin America are not available. In this narrative review, our goal was to descriptively summarize the prevalence and features of SpA in...

    Authors: Gustavo Citera, Wilson Bautista-Molano, Ingris Peláez-Ballestas, Valderilio F. Azevedo, Risto A. Perich, José A. Méndez-Rodríguez, Mariel S. Cutri and Cecilia E. Borlenghi
    Citation: Advances in Rheumatology 2021 61:2
    Content type: Review Published on:

    The Letter to this article has been published in Advances in Rheumatology 2021 61:26

  12. Modifiable cardiovascular risk factors (MCRFs), such as those related to aerobic capacity, muscle strength, physical activity, and body composition, have been poorly studied in Takayasu arteritis (TAK). Theref...

    Authors: Alexandre Moura dos Santos, Rafael Giovani Misse, Isabela Bruna Pires Borges, Bruno Gualano, Alexandre Wagner Silva de Souza, Liliam Takayama, Rosa Maria R. Pereira and Samuel Katsuyuki Shinjo
    Citation: Advances in Rheumatology 2021 61:1
    Content type: Research Published on:

  13. Systemic sclerosis (SSc) is an autoimmune disease characterized by fibrosis of skin and lung as well as involvement of kidney, gastrointestinal system and heart. Aetiology and exact mechanism of disease is poo...

    Authors: Tugce Emiroglu Gedik, Hamit Kucuk, Berna Goker, Seminur Haznedaroglu, Hatice Pasaoglu, Ozkan Varan, Mehmet Akif Ozturk, Ozge Tugce Pasaoglu and Abdurrahman Tufan
    Citation: Advances in Rheumatology 2020 60:54
    Content type: Research Published on:

  14. Adverse drug reactions (ADRs) are the sixth leading causes of death worldwide; monitoring them is fundamental, especially in patients with disorders like chronic rheumatic diseases (CRDs). The study aimed to d...

    Authors: Manar Amanouil Said, Liana Soido Teixeira e Silva, Aline Maria de Oliveira Rocha, Gustavo Guimarães Barreto Alves, Daniela Gerent Petry Piotto, Claudio Arnaldo Len and Maria Teresa Terreri
    Citation: Advances in Rheumatology 2020 60:53
    Content type: Research Published on:

  15. Gout is characterized by inflammatory arthritis with hyperuricaemia and deposition of monosodium urate (MSU) crystals in the joints. Several animal models have been proposed based on MSU crystals injection or ...

    Authors: Xiaoying Lin, Tiejuan Shao, Xianghui Wen, Mingzhu Wang, Chengping Wen and Zhixing He
    Citation: Advances in Rheumatology 2020 60:52
    Content type: Research Published on:

  17. The COVID-19 outbreak caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a global major concern. In this review, we addressed a theoretical model on immunopathogenesis associated...

    Authors: Bruno Bordallo, Mozart Bellas, Arthur Fernandes Cortez, Matheus Vieira and Marcelo Pinheiro
    Citation: Advances in Rheumatology 2020 60:50
    Content type: Review Published on:

  18. Psoriatic arthritis (PsA) is a chronic inflammatory disease of widely varying presentation, which determines functional and psychological impairment, with a high negative impact on patients’ quality of life.

    Authors: Elziane da Cruz Ribeiro e Souza, Sueli Coelho da Silva Carneiro, Michel Alexandre Yazbek, Rita de Cássia Menin, Cristiano Barbosa Campanholo, Jamille Nascimento Carneiro, Carlos Henrique Martis da Silva and Roberto Ranza
    Citation: Advances in Rheumatology 2020 60:49
    Content type: Research Published on:

  19. The reproducibility and reliability of the modified Rodnan’s Skin Score (mRSS) are debated due to investigator-related subjectivity. Here, we evaluate if durometry correlates with mRSS in patients with diffuse...

    Authors: Marília de Fátima Cirioli de Oliveira, Vanessa Cristina Leopoldo, Karla Ribeiro Costa Pereira, Daniela Aparecida de Moraes, Juliana Bernardes Elias Dias, Maynara Santana Gonçalves, Leandra Naíra Zambelli Ramalho, Bruna Nogueira dos Santos, Maria Carolina de Oliveira and Renata Cristina Campos Pereira Silveira
    Citation: Advances in Rheumatology 2020 60:48
    Content type: Research Published on:

  20. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Alex Domingos Reis, Cristiane Mudinutti, Murilo de Freitas Peigo, Lucas Lopes Leon, Lilian Tereza Lavras Costallat, Claudio Lucio Rossi, Sandra Cecília Botelho Costa and Sandra Helena Alves Bonon
    Citation: Advances in Rheumatology 2020 60:47
    Content type: Correction Published on:

    The original article was published in Advances in Rheumatology 2020 60:42

  21. Chronic low back pain (CLBP) represents a problem in the occupational environment, often associated with disability, sick-leave demands, loss of productivity, anxiety, depression and high socioeconomic cost. T...

    Authors: Aloma A. Feitosa, Edson Amaro Junior, Liana Guerra Sanches, Eduardo Ferreira Borba, Liliana Lourenço Jorge and Ari Stiel Radu Halpern
    Citation: Advances in Rheumatology 2020 60:46
    Content type: Research Published on:

  22. Anti-ribosomal P (anti-Rib-P) antibody is a specific serological marker for systemic lupus erythematosus (SLE) and routinely tested by targeting the common epitope of three ribosomal proteins of P0, P1 and P2....

    Authors: Zhen-rui Shi, Yan-fang Han, Jing Yin, Yu-ping Zhang, Ze-xin Jiang, Lin Zheng, Guo-zhen Tan and Liangchun Wang
    Citation: Advances in Rheumatology 2020 60:45
    Content type: Research Published on:

  24. Methotrexate (MTX) intolerance is frequent, and its early identification may impact treatment, leading to timely changes in medication that may promote patient compliance and better control of rheumatoid arthr...

    Authors: Jéssica Martins Amaral, Maria José Menezes Brito and Adriana Maria Kakehasi
    Citation: Advances in Rheumatology 2020 60:43
    Content type: Research Published on:

  25. Human herpesviruses (HHVs) are responsible for a significant number of clinical manifestations in systemic lupus erythematous (SLE) patients. The aim of this study was to determine the frequency of active HHV ...

    Authors: Alex Domingos Reis, Cristiane Mudinutti, Murilo de Freitas Peigo, Lucas Lopes Leon, Lilian Tereza Lavras Costallat, Claudio Lucio Rossi, Sandra Cecília Botelho Costa and Sandra Helena Alves Bonon
    Citation: Advances in Rheumatology 2020 60:42
    Content type: Research Published on:

    The Correction to this article has been published in Advances in Rheumatology 2020 60:47

  26. Hand osteoarthritis (HOA) is a complex disorder with various subtypes characterized with predominance of different features. It is challenging to estimate the severity of hand disability in HOA, since contribu...

    Authors: Nurhan Güven, Fitnat Dinçer, Alp Çetin and Serdar Can Güven
    Citation: Advances in Rheumatology 2020 60:41
    Content type: Research Published on:

  27. It is known that physical activity and muscular performance are reduced in fibromyalgia (FM) syndrome. This study aims to compare the performance of trunk muscles in women with FM and healthy controls and eval...

    Authors: Cevriye Mülkoğlu, Sühan Taşkın, Seçil Vural, Başak Mansız Kaplan, Ahmet Buğra Selvi and Hakan Genç
    Citation: Advances in Rheumatology 2020 60:40
    Content type: Research Published on:

  28. Fibromyalgia (FM) is a musculoskeletal chronic pain syndrome that impacts negatively patient’s daily lives. Its pathogenesis is characterized by a complex relationship between biological and psychosocial facto...

    Authors: Camila Fernanda da Silveira Alves, Wolnei Caumo, Joana Morez Silvestri, Maxciel Zortea, Vinicius Souza dos Santos, Dayane Favarin Cardoso, Andrea Regner, Alessandra Hübner de Souza and Daniel Simon
    Citation: Advances in Rheumatology 2020 60:39
    Content type: Research Published on:

  29. Annexins are a group of conserved proteins which exert several regulatory functions on various cellular activities. Increased frequency and levels of antibodies against annexin V have already been observed in ...

    Authors: Alex Magno Coelho Horimoto, Laize Guerreiro de Jesus, Albert Schiaveto de Souza, Silvia Helena Rodrigues and Cristiane Kayser
    Citation: Advances in Rheumatology 2020 60:38
    Content type: Research Published on:

  30. To verify the validity of the 2016-revised Fibromyalgia Survey Questionnaire (FSQ) by telephone interview compared to self-administration and to produce a valid version of FSQ in Brazilian Portuguese language.

    Authors: Jordana Bernardi Daltrozo, Juliane Aline Paupitz and Fabricio Souza Neves
    Citation: Advances in Rheumatology 2020 60:37
    Content type: Research Published on:

  31. Juvenile Idiopathic Arthritis (JIA) and its related symptoms (e.g. pain) have been associated with interference in the daily life of adolescents with JIA including their friendships. There is little research i...

    Authors: Imma Beneitez, Rubén Nieto, Eulàlia Hernández and Mercè Boixadós
    Citation: Advances in Rheumatology 2020 60:36
    Content type: Research Published on:

  32. Duloxetine and amitriptyline are antidepressants used in the treatment of fibromyalgia. In published systematic reviews, there is no agreement about which drug is more effective and safer. This study aimed to ...

    Authors: Áurea Dias de Farias, Luciana Eberle, Tânia Alves Amador and Tatiane da Silva Dal Pizzol
    Citation: Advances in Rheumatology 2020 60:35
    Content type: Research Published on:

  33. Fibromyalgia Syndrome (FMS), is a chronic pain disorder with poorly understood pathophysiology. In recent years, repetitive transcranial magnetic stimulation (rTMS) has been recommended for pain relief in vari...

    Authors: Suman Tanwar, Bhawna Mattoo, Uma Kumar and Renu Bhatia
    Citation: Advances in Rheumatology 2020 60:34
    Content type: Research Published on:

  34. The severity of nail disease, the presence of arthralgia and fatigue are predictors of development of psoriatic arthritis (PsA) in patients with psoriasis (Pso). In children, little is known about the musculos...

    Authors: Thaís Cugler Meneghetti, Thaís Mayumi Honda Padilha, Valderílio Feijó Azevedo, Mônica Nunes Lima Cat, Bruna Maria Stofela Sarolli and Vânia Oliveira de Carvalho
    Citation: Advances in Rheumatology 2020 60:33
    Content type: Research Published on:

  35. Hydroxychloroquine and chloroquine, also known as antimalarial drugs, are widely used in the treatment of rheumatic diseases and have recently become the focus of attention because of the ongoing COVID-19 pand...

    Authors: Edgard Torres dos Reis Neto, Adriana Maria Kakehasi, Marcelo de Medeiros Pinheiro, Gilda Aparecida Ferreira, Cláudia Diniz Lopes Marques, Licia Maria Henrique da Mota, Eduardo dos Santos Paiva, Gecilmara Cristina Salviato Pileggi, Emília Inoue Sato, Ana Paula Monteiro Gomides Reis, Ricardo Machado Xavier and José Roberto Provenza
    Citation: Advances in Rheumatology 2020 60:32
    Content type: Position article and guidelines Published on:

  36. Evaluating small nerve fibers in patients with systemic lupus erythematosus (SLE) using cutaneous silent period (CSP) and skin biopsy and assesssing the relationship between clinical signs, autoantibodies and ...

    Authors: Aslan Tekatas, Demet Deniz Tekatas, Volkan Solmaz, Turan Karaca and Omer Nuri Pamuk
    Citation: Advances in Rheumatology 2020 60:31
    Content type: Research Published on:

  37. The inadequate storage of biopharmaceuticals may result in an ineffective therapeutic response since poor conservation can lead to the emergence of protein aggregates and cause immunogenicity in patients, whic...

    Authors: Glaucia Santin, Mariana Moreira Magnabosco da Silva, Vinicius Augusto Villarreal, Leane Dhara Dalle Laste, Eduardo de Freitas Montin, Luis Eduardo Ribeiro Betiol and Valderilio Feijó Azevedo
    Citation: Advances in Rheumatology 2020 60:30
    Content type: Research Published on:

  38. The term Direct Oral Anticoagulants (DOACs) refers to a group of drugs that inhibit factor Xa or thrombin. Even though their use for treating different thrombotic or prothrombotic conditions is increasing rece...

    Authors: Gustavo Guimarães Moreira Balbi, Marcelo de Souza Pacheco, Odirlei Andre Monticielo, Andreas Funke, Adriana Danowski, Mittermayer Barreto Santiago, Henrique Luiz Staub, Jozelia Rêgo and Danieli Castro Oliveira de Andrade
    Citation: Advances in Rheumatology 2020 60:29
    Content type: Position article and guidelines Published on:

  39. Rheumatoid arthritis (RA) is an inflammatory and chronic autoimmune disease that leads to muscle mass loss and functional capacity impairment, potentiated by physical inactivity. Despite evidences demonstrate ...

    Authors: Denise Blum, Rodrigo Rodrigues, Jeam Marcel Geremia, Claiton Viegas Brenol, Marco Aurélio Vaz and Ricardo Machado Xavier
    Citation: Advances in Rheumatology 2020 60:28
    Content type: Research Published on:

  40. To translate and cross-culturally adapt the Home Falls and Accidents Screening Tool Self-report into Brazilian Portuguese and to correlate with the history of falls.

    Authors: Jarbas Melo Filho, Natacha Verônica Bazanella, Audrin Said Vojciechowski, Elisiê Rossi Ribeiro Costa, Lynette Mackenzie and Anna Raquel Silveira Gomes
    Citation: Advances in Rheumatology 2020 60:27
    Content type: Research Published on:

  41. Injection of Hylan G-F20 (HY) into joints may provoke local flares, which mechanisms may involve reaction to protein contaminants. We have previously developed a protein-free saline-soluble galactomannan deriv...

    Authors: Rodolfo de Melo Nunes, Pablyana Leila Rodrigues Cunha, Ana Carolina Matias Dinelly Pinto, Virgínia Claudia Carneiro Girão, Judith Pessoa de Andrade Feitosa and Francisco Airton Castro Rocha
    Citation: Advances in Rheumatology 2020 60:26
    Content type: Research Published on:

  42. Currently, magnetic resonance imaging (MRI) is used to evaluate active inflammatory sacroiliitis related to axial spondyloarthritis (axSpA). The qualitative and semiquantitative diagnosis performed by expert r...

    Authors: Matheus Calil Faleiros, Marcello Henrique Nogueira-Barbosa, Vitor Faeda Dalto, José Raniery Ferreira Júnior, Ariane Priscilla Magalhães Tenório, Rodrigo Luppino-Assad, Paulo Louzada-Junior, Rangaraj Mandayam Rangayyan and Paulo Mazzoncini de Azevedo-Marques
    Citation: Advances in Rheumatology 2020 60:25
    Content type: Research Published on:

  46. The mat Pilates method is the therapeutic modalities which can be used in fibromyalgia treatment. Although there are no well-designed studies that prove the effectiveness of the mat Pilates method in this popu...

    Authors: Suzy Araújo de Medeiros, Hugo Jário de Almeida Silva, Rayssa Maria do Nascimento, Jaely Beatriz da Silva Maia, Caio Alano de Almeida Lins and Marcelo Cardoso de Souza
    Citation: Advances in Rheumatology 2020 60:21
    Content type: Research Published on:

  47. In Brazil, socioeconomic differences in the incidence of rheumatoid arthritis (RA) have been demonstrated, which are important in the formulation of hypotheses regarding the association between environmental f...

    Authors: Nathália de Carvalho Sacilotto, Rina Dalva Neubarth Giorgi, Ana Beatriz Vargas-Santos, Cleandro Pires de Albuquerque, Sebastião Cezar Radominski, Ivânio Alves Pereira, Maria Fernanda Brandão Resende Guimarães, Manoel Barros Bértolo, Paulo Louzada Jr, Maria de Fátima Lobato da Cunha Sauma, Karina Rossi Bonfiglioli, Claiton Viegas Brenol, Licia Maria Henrique da Mota and Geraldo da Rocha Castelar-Pinheiro
    Citation: Advances in Rheumatology 2020 60:20
    Content type: Research Published on:

  48. Correlate serum magnesium (Mg) and Calcium (Ca) levels with body composition and metabolic parameters in women with fibromyalgia (FM).

    Authors: Aline Andretta, Maria Eliana Madalozzo Schieferdecker, Ricardo Rasmussen Petterle, Eduardo dos Santos Paiva and César Luiz Boguszewski
    Citation: Advances in Rheumatology 2020 60:18
    Content type: Research Published on:

  49. Takayasu’s arteritis (TA) affects young women in the childbearing age group. We studied obstetric outcomes in these patients before and after disease onset.

    Authors: Latika Gupta, Durga Prasanna Misra, Sakir Ahmed, Avinash Jain, Abhishek Zanwar, Able Lawrence, Vikas Agarwal, Amita Aggarwal and Ramnath Misra
    Citation: Advances in Rheumatology 2020 60:17
    Content type: Research Published on:

  50. Last decades witnessed great technological advances in rheumatoid arthritis (RA) management, but their implementation in clinical practice might prove difficult. Despite the efficacy demonstrated in controlled...

    Authors: Ana Paula Monteiro Gomides, Cleandro Pires de Albuquerque, Ana Beatriz Vargas Santos, Manoel Barros Bértolo, Paulo Louzada Júnior, Rina Dalva Neubarth Giorgi, Sebastião Cezar Radominski, Maria Fernanda B. Resende Guimarães, Karina Rossi Bonfiglioli, Maria de Fátima Lobato da Cunha Sauma, Ivânio Alves Pereira, Claiton Viegas Brenol, Licia Maria Henrique da Mota and Geraldo da Rocha Castelar Pinheiro
    Citation: Advances in Rheumatology 2020 60:16
    Content type: Research Published on:
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Advances in Rheumatology

ISSN: 2523-3106