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  1. Nail psoriasis occurs frequently in patients with psoriatic disease, it can lead to functional impairment, pain, discomfort, decreased quality of life and can also be a predictor for the development of arthrit...

    Authors: Samanta Daiana De Rossi, José Alexandre Mendonça, Penelope Ester Palominos, Charles Lubianca Kohem, Tania Ferreira Cestari and Rafael Mendonça da Silva Chakr

    Citation: Advances in Rheumatology 2021 61:48

    Content type: Research

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  2. To evaluate the quality of referrals for a first Rheumatology consultation at a tertiary care center in a southern Brazilian capital (Porto Alegre, RS), having as background findings from a similar survey perf...

    Authors: Deise Marcela Piovesan, Vanessa Barrili Busato, Romulo Gomes da Silveira, Aline Defaveri do Prado, Cynthia Goulart Molina-Bastos, Sheila Hickmann, Guilherme Kopik Bongiorno, Camila de David Cruz, Sheron Zamboni, Julio César Simon, Marcelo Rodrigues Gonçalves and Markus Bredemeier

    Citation: Advances in Rheumatology 2021 61:47

    Content type: Research

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  3. Infections are a major cause of morbidity and mortality in systemic lupus (SLE). Vaccination would be an effective method to reduce infection rate. Coverage for influenza and pneumococcus appears to be low in ...

    Authors: Edson Hernán Chiganer, Bruno Camargo Ochi and Carmen Flora Lessa

    Citation: Advances in Rheumatology 2021 61:46

    Content type: Research

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  4. As the coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to spread rapidly, there are still many unresolved questions of how this vir...

    Authors: Piero Ruscitti, Alessandro Conforti, Paola Cipriani, Roberto Giacomelli, Marco Tasso, Luisa Costa and Francesco Caso

    Citation: Advances in Rheumatology 2021 61:45

    Content type: Review

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  5. The protein chitinase-3-like-1 (YKL-40) is rarely analyzed in patients with myositis. Therefore, we aimed to evaluate YKL-40 serum levels; correlate them with laboratory and clinical parameters, disease status...

    Authors: Renata Casseb de Souza Carboni, Gustavo Luiz Behrens Pinto and Samuel Katsuyuki Shinjo

    Citation: Advances in Rheumatology 2021 61:44

    Content type: Research

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  6. Systemic Lupus Erythematosus (SLE) is an autoimmune disease, characterized by being multi-systemic and, therefore, reaching various organs and affecting mainly young women. Its pathogenesis comprehends many fa...

    Authors: Juliana Rosa Pires Vieira, Andréa Toledo de Oliveira Rezende, Marcos Rassi Fernandes and Nilzio Antonio da Silva

    Citation: Advances in Rheumatology 2021 61:42

    Content type: Research

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  7. During the COVID-19 pandemic, individuals faced psychological stress caused by fear and anxiety due to the high transmission and mortality rate of the disease, the social isolation, economic problems, and diff...

    Authors: Damla Cankurtaran, Nihal Tezel, Buse Ercan, Sadik Yigit Yildiz and Ece Unlu Akyuz

    Citation: Advances in Rheumatology 2021 61:41

    Content type: Research

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  8. Juvenile idiopathic arthritis (JIA) can cause reduced exercise capacity, deterioration in functional activities, and poor health-related quality of life. This study aims to objectively reveal lower extremity i...

    Authors: Sevtap Acer Kasman, Özgür Zeliha Karaahmet, Ajda Bal Hastürk, Özge Başaran, Banu Çelikel Acar, Halise Hande Gezer and Aytül Çakcı

    Citation: Advances in Rheumatology 2021 61:39

    Content type: Research

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  9. Rheumatoid arthritis (RA) is a common autoimmune systemic inflammatory disease. In addition to joint involvement, RA patients frequently have other comorbidities, such as cardiovascular diseases. Drugs used fo...

    Authors: Gustavo Nogueira Schincariol Vicente, Ivânio Alves Pereira, Gláucio Ricardo Werner de Castro, Licia Maria Henrique da Mota, Ana Paula Carnieletto, Dhara Giovanna Santin de Souza, Fabiana Oenning da Gama, Ana Beatriz Vargas Santos, Cleandro Pires de Albuquerque, Manoel Barros Bértolo, Paulo Louzada Júnior, Rina Dalva Neubarth Giorgi, Sebastião Cezar Radominski, Maria Fernanda Brandão Resende Guimarães, Karina Rossi Bonfiglioli, Maria de Fátima Lobato da Cunha Sauma…

    Citation: Advances in Rheumatology 2021 61:38

    Content type: Research

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  10. To investigate the diagnostic performance of single-source dual-energy computed tomography (DECT) based on gemstone spectral imaging technology (including Discovery CT750HD and Revolution CT) in patients with ...

    Authors: Jin Shang, Xiao-Hu Li, Shu-Qin Lu, Yi Shang, Lu-Lu Li and Bin Liu

    Citation: Advances in Rheumatology 2021 61:36

    Content type: Research

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  11. Trunk pelvic dissociation is fundamental to the compensatory mechanism for muscle weakness during body bending. We carried out an early investigation of gait changes in a sample of community-dwelling women ≥60...

    Authors: Leda Magalhaes Oliveira, Suely Roizenblatt, Flavio Duarte Silva, Arnaldo Roizenblatt, Artur Rocha Correa Fernandes and Vera Lucia Szejnfeld

    Citation: Advances in Rheumatology 2021 61:35

    Content type: Research

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  12. Systemic sclerosis (SSc) is a chronic disease characterized by autoimmunity, vasculopathy, and visceral and cutaneous fibrosis. Vitamin D has several functions in the immunological system, and different studie...

    Authors: Laiana Schneider, Vanessa Hax, Odirlei Monticielo, Tamires Ferri Macedo, Roberta Kern Menna Barreto, Natália Aydos Marcondes and Rafael Chakr

    Citation: Advances in Rheumatology 2021 61:34

    Content type: Research

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  13. Vasculitis damage index (VDI) is a validated damage index for systemic vasculitis, and as Behçet’s disease is considered one of systemic vascular disease we aimed to study the relationship of the vasculitis da...

    Authors: Fatema T. Elgengehy, Sherif M. Gamal, Nesreen Sobhy, Ibrahem Siam, Ahmed M. Soliman, Ghada W. Elhady and Tamer A. Gheita

    Citation: Advances in Rheumatology 2021 61:33

    Content type: Research

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  14. To evaluate the perception of rheumatologists regarding the recommendations of the Brazilian Consensus for detection of Autoantibodies (BCA) on HEp-2 Cells by Indirect Immunofluorescence assay (IFA) and how BC...

    Authors: Isadora Carvalho Medeiros Francescantonio, Leandro Augusto Rodrigues dos Santos, Paulo Luiz Carvalho Francescantonio, Luiz Eduardo Coelho Andrade and Wilson de Melo Cruvinel

    Citation: Advances in Rheumatology 2021 61:32

    Content type: Research

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  15. Osteoarthritis (OA) is defined as a degenerative disease. Pivotal roles of long non-coding RNA (lncRNAs) in OA are widely elucidated. Herein, we intend to explore the function and molecular mechanism of lncRNA...

    Authors: Binfeng Wang and Xiangwei Liu

    Citation: Advances in Rheumatology 2021 61:31

    Content type: Research

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  16. The Functional Index for Hand Osteoarthritis (FIHOA) is a simple, reliable, and reproducible specific instrument to evaluate hand OA that can be applied both in clinical practice and research protocols. In ord...

    Authors: Francisco Vileimar Andrade de Azevedo, Hermano Alexandre Lima Rocha, Anamaria Jones, Jamil Natour and Francisco Airton Castro da Rocha

    Citation: Advances in Rheumatology 2021 61:30

    Content type: Research

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    The Correction to this article has been published in Advances in Rheumatology 2021 61:37

  17. Familial Mediterranean fever (FMF) is an autoinflammatory disease characterized by recurrent episodes of fever and serositis. Sacroiliitis can be observed in some FMF patients. This study aimed to compare the ...

    Authors: Hülya Kaçmaz, Esin Aldemir, Ayşe Tanatar, Şerife Gül Karadağ, Mustafa Çakan, Hafize Emine Sönmez and Nuray Aktay Ayaz

    Citation: Advances in Rheumatology 2021 61:29

    Content type: Research

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  18. Few studies have evaluated the relation of quality of life (QoL) with symptoms and disease activity in primary Sjögren’s syndrome (pSS). There is also scant information on the predictors of QoL in this populat...

    Authors: Laiza Hombre Dias, Samira Tatiyama Miyamoto, Raquel Altoé Giovelli, Caerê Iamonde Maciel de Magalhães and Valeria Valim

    Citation: Advances in Rheumatology 2021 61:28

    Content type: Research

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  19. Systemic sclerosis (SSc) is a chronic autoimmune disease characterized by vasculopathy and fibrosis, which can be subclassified into diffuse cutaneous (dSSc) and limited cutaneous (lSSc) subtypes. Previous stu...

    Authors: Laiana Schneider, Natália Aydos Marcondes, Vanessa Hax, Isadora Flesch da Silva Moreira, Carolina Yuka Ueda, Rafaella Romeiro Piovesan, Ricardo Xavier and Rafael Chakr

    Citation: Advances in Rheumatology 2021 61:27

    Content type: Research

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  20. The Val66Met polymorphism of the brain-derived neurotrophic factor (BDNF) gene is a potential biomarker of vulnerability to pain. Thus, the present study aimed to investigate the association of this polymorphi...

    Authors: Angela Shiratsu Yamada, Flavia Tasmim Techera Antunes, Camila Ferraz, Alessandra Hubner de Souza and Daniel Simon

    Citation: Advances in Rheumatology 2021 61:24

    Content type: Research

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  21. Chronic prostatitis has been a common disease reported with high frequency in ankylosing spondylitis (AS) even from decades ago. Infectious (Chlamydia trachomatis) or non-infectious (uric acid) prostatitis can hy...

    Authors: Eduardo Deves, Rodrigo Novotny, Fernando Hartmann Barazzetti, Mara Cristina Scheffer, Letícia Kramer Pacheco, Adriana Fontes Zimmermann, Ivânio Alves Pereira, Maria Luiza Bazzo and Fabricio Souza Neves

    Citation: Advances in Rheumatology 2021 61:23

    Content type: Research

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  22. Hepatitis B virus (HBV) reactivation consequent to immunosuppressive therapy is an increasingly prevalent problem with serious clinical implications. Treatment with biologic agents conduces to the loss of prot...

    Authors: Ming-Hui Hung, Ya-Chih Tien and Ying-Ming Chiu

    Citation: Advances in Rheumatology 2021 61:22

    Content type: Research

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  23. The most important finding that affects the prognosis in Familial Mediterranean Fever is renal amyloidosis. The aim of the present study was to analyze neutrophil gelatinase-associated lipocalin levels in the ...

    Authors: Sinem Can Oksay, Hasan Dursun, Sebnem Tekin Neijmann and Sami Hatipoglu

    Citation: Advances in Rheumatology 2021 61:20

    Content type: Research

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  24. This study identified whether Functional Index for Hand Osteoarthritis (FIHOA) is associated with pain, hand muscle strength, health-related quality of life, and radiographic severity in hand osteoarthritis (OA).

    Authors: Seong-Kyu Kim, Ui Hong Jung and Jung-Yoon Choe

    Citation: Advances in Rheumatology 2021 61:19

    Content type: Research

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  25. To investigate the associations between sleep quality, fatigue, disease activity and depressive symptoms in women with rheumatoid arthritis (RA).

    Authors: Fernando Henrique Azevedo Lopes, Max Victor Carioca Freitas, Veralice Meireles Sales de Bruin and Pedro Felipe Carvalhedo de Bruin

    Citation: Advances in Rheumatology 2021 61:18

    Content type: Research

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  26. Hyperhomocysteinemia is associated with autoimmune diseases such as ankylosing spondylitis (AS), systemic lupus erythematosus (SLE), and rheumatoid arthritis (RA). Current findings regarding plasma/serum homoc...

    Authors: Hui-hui Li, Xue-quan Li, Lin-tao Sai, Yi Cui, Jia-hui Xu, Chi Zhou, Jing Zheng, Xing-fu Li, Hua-xiang Liu and Ying-jie Zhao

    Citation: Advances in Rheumatology 2021 61:17

    Content type: Research

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  27. Systemic sclerosis (SSc) is a clinically complex and challenging disease, that leads to skin fibrosis. Its most frequent complication is interstitial lung disease (ILD), which leads to a worse prognosis. In th...

    Authors: Marina Maria Vieira de Figueiredo Caldas, Kesley Pablo Morais de Azevedo, Ana Clara de França Nunes, Victor Hugo de Oliveira, Isac Davidson Santiago Fernandes Pimenta, Isabela Dantas Torres de Araújo, Francisco Alves Bezerra Neto, Ana Katherine da Silveira Gonçalves de Oliveira and Grasiela Piuvezam

    Citation: Advances in Rheumatology 2021 61:15

    Content type: Research

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  28. The objective of this paper is to analyze the prices of biological drugs in the treatment of Rheumatoid Arthritis (RA) in three Latin American countries (Brazil, Colombia and Mexico), as well as in Spain and t...

    Authors: Gabriela Bittencourt Gonzalez Mosegui, Fernando Antõnanzas, Cid Manso de Mello Vianna and Paula Rojas

    Citation: Advances in Rheumatology 2021 61:14

    Content type: Review

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  29. Psoriatic arthritis (PsA) is a multifaceted inflammatory disease that can cause joint destruction and impair quality of life. The Psoriatic Arthritis Quality of Life Questionnaire (PsAQoL) was the first diseas...

    Authors: Rafaela Silva Guimaraes Gonçalves, Alice Heaney, Stephen P. McKenna, Jonas Braynner Carvalho, Maria Eduarda Lima Vidal, Marina Coelho Mores de Brito and Angela Luzia Branco Pinto Duarte

    Citation: Advances in Rheumatology 2021 61:13

    Content type: Research

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  30. Sickle cell disease (SCD) is an autosomal recessive genetic disease in which a mutation occurs in the β-globin chain gene, resulting in abnormal hemoglobin levels. In an environment with reduced oxygen concent...

    Authors: Taciana Fernandes Araújo Ferreira, Ana Paula Teixeira dos Santos, Alexandra Silva Leal, Gilberto de Araújo Pereira, Sheila Soares Silva and Helio Moraes-Souza

    Citation: Advances in Rheumatology 2021 61:11

    Content type: Research

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  31. Fibromyalgia is a chronic pain disorder characterized by widespread musculoskeletal symptoms, primarily attributed to sensitization of somatosensory system carrying pain. Few reports have investigated the impa...

    Authors: Vikas Kumar Tiwari, Srishti Nanda, Suvercha Arya, Uma Kumar, Ratna Sharma, Senthil S. Kumaran and Renu Bhatia

    Citation: Advances in Rheumatology 2021 61:10

    Content type: Research

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  32. In the past 20 years, hematopoietic stem cell transplantation (HSCT) has been investigated as treatment for systemic sclerosis (SSc). The goal of HSCT is to eradicate the autoreactive immune system, which is r...

    Authors: Álvaro Henrique-Neto, Marianna Yumi Kawashima Vasconcelos, Juliana Bernardes Elias Dias, Daniela Aparecida de Moraes, Maynara Santana Gonçalves, Djúlio César Zanin-Silva, Talita Graminha Zucoloto, Marília de Fátima Cirioli de Oliveira, Giuliana Martinelli Dotoli, Luiz Fernando Weffort, Vanessa Cristina Leopoldo and Maria Carolina Oliveira

    Citation: Advances in Rheumatology 2021 61:9

    Content type: Research

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  33. Sjögren’s Syndrome compromises the exocrine function, producing xerostomia and xerophthalmia. It can appear as an isolated condition or associated with other autoimmune diseases (polyautoimmunity). The Unstimu...

    Authors: María Alejandra Martínez-Ceballos, Natalia Aguilera, Kenny Carolina Garzón-González, Jairo Cajamarca-Baron, Juan Pablo Alzate-Granados and Adriana Rojas-Villarraga

    Citation: Advances in Rheumatology 2021 61:8

    Content type: Research

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  34. To compare the efficacy and safety of a new formulation of a fixed dose combination of glucosamine sulfate (GS; 1500 mg) and bovine chondroitin sulfate (CS; 1200 mg) versus the reference product (RP) in patien...

    Authors: Andrea Barranjard Vannucci Lomonte, Emerson Gimenez, Antônio Carlos da Silva, Sebastião Cezar Radominski, Morton Aaron Scheinberg, Antônio Carlos Ximenes and Cristiano Augusto de Freitas Zerbini

    Citation: Advances in Rheumatology 2021 61:7

    Content type: Research

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  35. Complementary and alternative medicine (CAM) use is prevalent among patients living with arthritis. Such patients often seek information online, for the purpose of gaining a second opinion to their healthcare ...

    Authors: Jeremy Y. Ng, Alexandra Vacca and Tanya Jain

    Citation: Advances in Rheumatology 2021 61:6

    Content type: Research

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  36. Abdominal symptoms in patients with primary Sjögren syndrome (pSS) are poorly documented. The objective of the study was to describe the abdominal symptoms of patients with pSS and to assess their association ...

    Authors: Simon Parreau, Jérémie Jacques, Stéphanie Dumonteil, Sylvain. Palat, Sophie Geyl, Guillaume Gondran, Holy Bezanahary, Eric Liozon, Julie Azaïs, Stéphanie Colombie, Marie-Odile Jauberteau, Véronique Loustaud-Ratti, Kim-Heang Ly and Anne-Laure Fauchais

    Citation: Advances in Rheumatology 2021 61:5

    Content type: Research

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  37. Spondyloarthritis (SpA) is a group of chronic inflammatory systemic diseases characterized by axial and/or peripheral joints inflammation, as well as extra-articular manifestations. Over some decades, nonstero...

    Authors: Ricardo da Cruz Lage, Claudia Diniz Lopes Marques, Thauana Luiza Oliveira, Gustavo Gomes Resende, Charles Lubianca Kohem, Carla Gonçalves Saad, Antônio Carlos Ximenes, Célio Roberto Gonçalves, Washington Alves Bianchi, Eduardo de Souza Meirelles, Mauro Waldemar Keiserman, Adriano Chiereghin, Cristiano Barbosa Campanholo, André Marun Lyrio, Cláudia Goldenstein Schainberg, Lenise Brandao Pieruccetti…

    Citation: Advances in Rheumatology 2021 61:4

    Content type: Position article and guidelines

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  38. Whole-body cryotherapy (WBC) has shown to be beneficial in the treatment of fibromyalgia (FM). There is cumulative evidence that cytokines play a crucial role in FM. It’s unknown whether clinical effects of WB...

    Authors: Philipp Klemm, Johanna Becker, Iris Aykara, Thomas Asendorf, Gabriel Dischereit, Elena Neumann, Ulf Müller-Ladner and Uwe Lange

    Citation: Advances in Rheumatology 2021 61:3

    Content type: Research

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  39. Large epidemiologic and clinical estimates of spondyloarthritis (SpA) in Latin America are not available. In this narrative review, our goal was to descriptively summarize the prevalence and features of SpA in...

    Authors: Gustavo Citera, Wilson Bautista-Molano, Ingris Peláez-Ballestas, Valderilio F. Azevedo, Risto A. Perich, José A. Méndez-Rodríguez, Mariel S. Cutri and Cecilia E. Borlenghi

    Citation: Advances in Rheumatology 2021 61:2

    Content type: Review

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    The Letter to this article has been published in Advances in Rheumatology 2021 61:26

  40. Modifiable cardiovascular risk factors (MCRFs), such as those related to aerobic capacity, muscle strength, physical activity, and body composition, have been poorly studied in Takayasu arteritis (TAK). Theref...

    Authors: Alexandre Moura dos Santos, Rafael Giovani Misse, Isabela Bruna Pires Borges, Bruno Gualano, Alexandre Wagner Silva de Souza, Liliam Takayama, Rosa Maria R. Pereira and Samuel Katsuyuki Shinjo

    Citation: Advances in Rheumatology 2021 61:1

    Content type: Research

    Published on:

  41. Systemic sclerosis (SSc) is an autoimmune disease characterized by fibrosis of skin and lung as well as involvement of kidney, gastrointestinal system and heart. Aetiology and exact mechanism of disease is poo...

    Authors: Tugce Emiroglu Gedik, Hamit Kucuk, Berna Goker, Seminur Haznedaroglu, Hatice Pasaoglu, Ozkan Varan, Mehmet Akif Ozturk, Ozge Tugce Pasaoglu and Abdurrahman Tufan

    Citation: Advances in Rheumatology 2020 60:54

    Content type: Research

    Published on:

  42. Adverse drug reactions (ADRs) are the sixth leading causes of death worldwide; monitoring them is fundamental, especially in patients with disorders like chronic rheumatic diseases (CRDs). The study aimed to d...

    Authors: Manar Amanouil Said, Liana Soido Teixeira e Silva, Aline Maria de Oliveira Rocha, Gustavo Guimarães Barreto Alves, Daniela Gerent Petry Piotto, Claudio Arnaldo Len and Maria Teresa Terreri

    Citation: Advances in Rheumatology 2020 60:53

    Content type: Research

    Published on:

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