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Fig. 3 | Advances in Rheumatology

Fig. 3

From: Crosstalk between the JAK2 and TGF-β1 signaling pathways in scleroderma-related interstitial lung disease targeted by baricitinib

Fig. 3

The impacts of baricitinib on JAK2 phosphorylation and TGF-β1 expression in lung tissue in IF assay. A Immunofluorescence staining of p-JAK2 and TGF-β1 in the lung tissue among three groups. The left 4 pictures of each group are 200x, and the enlarged picture of each group is 630x. B Statistics of p-JAK2+ and TGF-β1+ cells in lung sections among groups (n = 3). Data are presented as the means ± SEM. * p < 0.05, ** p < 0.01, *** p < 0.001

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