Fig. 1

Baricitinib attenuates bleomycin-induced injury and fibrosis. A Changes in body weight over time in three groups of mice. *, bleomycin vs control group. #, baricitinib versus control group. $, bleomycin vs baricitinib group (n = 6). B The levels of lung weight ratios in three groups of mice (n = 6). C & D Lung and skin tissue sections were stained with HE and Masson’s trichrome. The left picture of each group is 100x, and the right enlarged picture of each group is 400x. Statistics of modified ashcroft scores of lung tissue (E) and dermal thickness of skin tissue (F) among groups in HE staining (n = 4). Statistics of lung (G) and skin (H) collagen content among groups in Masson’s trichrome staining (n = 4). Data are presented as the means ± SEM. */#/$ p < 0.05, **/## p < 0.01, ***/### p < 0.001