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Table 3 Comparative analysis of health-related quality of life in childhood-onset systemic lupus erythematosus patients with and without cognitive dysfunction (n = 39)

From: Cognitive dysfunction in patients with childhood-onset systemic lupus erythematosus may impact treatment

  

Memory

Visual-spatial processing

Language

Yes

No

p

Yes

No

p

Yes

No

p

WHOQOL- BEEF

Physical health

62.48

(35.7–75.0)

64.29

(42.9–82.1)

0.350

73.57

50.0–75.0

64.26

35.7–82.1

0.813

51.8

50.0-53.6

64.3

35.7–82.1

0.117

Environment

57.85

40.6–84.4

68.75

72.8–87.5

0.030

62.50

46.9–71.9

60.94

40.6–87.5

0.962

53.1

46.9–59.4

62.5

40.63–87.5

0.237

Psychological

70.83

41.7–83.3

66.67

41.7–79.2

0.756

70.83

50.0-79.2

66.67

41.7–83.3

0.336

54.2

50.0-58.3

70.8

41.7–83.3

0.095

Social relationship

75.0

41.7–100.0

83.33

33.3–100.0

0.213

75.0

66.7–100.0

75.0

33.30–100.0

0.924

75.0

66.7–83.3

75.0

33.3–100.0

0.796

SLEQOL

Treatment

11.0

4.0–18.0

6.0

4.0–13.0

0.010

8.0

4.0–12.0

9.5

4.0–18.0

0.329

8.0

4–12

9.0

4–18

0.720

Physical function

8.0

6.0–28.0

8.0

6.0–29.0

0.798

9.0

6.0–28.0

8.0

6.0–29.0

0.330

17.0

6–28

8.0

6–29

0.713

Symptoms

15.5

8.0–32.0

12.0

8.0–23.0

0.211

16.0

8.0–21.0

12.5

8.0–32.0

0.601

18.5

16.0–21.0

13.0

8.0–32.0

0.282

Mood

9.0

4.0–26.0

6.0

4.0–19.0

0.310

10.0

4.0–12.0

7.0

4.0–26.0

0.905

8.0

4.0–12.0

7.0

4.0–24.0

0.694

Self-image

15.5

9.0–48.0

13.0

9.0–27.0

0.267

15.0

12.0–29.0

15.0

9.0–48.0

0.687

20.0

11.0–29.0

15.0

9.0–48.0

0.803

Occupational activity

19.0

9.0–52.0

15.0

9.0–39.0

0.539

25.0

9.0–43.0

15.0

9.0–52.0

0.245

29.0

15.0–43.0

17.0

9.0–52.0

0.334

 

GADL

26.0

14–26

26.0

24–26

0.851

23.4

14–26

25.93

24–26

0.008

19.0

14–24

26.0

25–26

0.000

  1. SLEQUOL - Systemic Lupus Erythematosus-specific quality-of-life instrument
  2. GADL: General Activities of Daily Living Scale;