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Table 1 General characteristics at disease onset and duration of follow-up

From: Comparison of clinical features, disease activity, treatment and outcomes between late-onset and early-onset patients with systemic lupus erythematosus. A sex- and year at diagnosis-matched controlled study

Variables

Late-onset SLE

(N = 62)

Early-onset SLE

(N = 124)

p value

Female, n (%)

54 (87.1)

114 (91.9)

0.303

Age at diagnosis in years, mean (95% CI)

56.3 (55.1–57.5)

30.9 (29.3–32.6)

 

Year of diagnosis

  

0.962

1990–1999, n (%)

2 (3.0)

5 (4.0)

 

2000–2009, n (%)

24 (39.0)

47 (38.0)

 

2010–2020, n (%)

36 (58.0)

72 (58.0)

 

Underlying disease

   

Hypertension, n (%)

18 (29.0)

1 (0.8)

< 0.001

Diabetes mellitus, n (%)

4 (6.5)

0

0.012

Dyslipidemia, n (%)

4 (6.5)

0

0.012

Chronic kidney disease, n (%)

3 (4.8)

0

0.036

Cerebrovascular disease, n (%)

4 (6.5)

0

0.012

Malignancy, n (%)

0

3 (2.4)

0.552

Duration of follow-up in years, mean (95% CI)a

4.4 (3.4–5.6)

6.3 (5.3–7.3)

0.019

  1. a = transformed data, SLE = systemic lupus erythematosus