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Fig. 4 | Advances in Rheumatology

Fig. 4

From: The role of proteasome in muscle wasting of experimental arthritis

Fig. 4

Treatments with etanercept and methotrexate reverse changes in proteasome subunits protein expression levels. GA muscle homogenates of arthritic and healthy animals were used for protein detection of A PSMβ5, B PSMβ5-induced, C PSMβ1, D PSMβ1-induced, and GAPDH by Western blot images. Protein levels are presented in % versus values of CO group. CIA-Vehicle: CIA with PBS; CIA-ETN: CIA treated with etanercept; CIA-MTX: CIA treated with methotrexate. Data were analyzed by one-way ANOVA followed by Tukey’s test and are presented as mean ± SEM; n = 8 animals per group. *p < 0.05; **p < 0.01

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