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Table 3 Meta-regression of BDNF levels in SLE patients and healthy controls

From: Blood levels of brain-derived neurotrophic factor (BDNF) in systemic lupus erythematous (SLE): a systematic review and meta-analysis

Moderator

No. of comparisons

No. of subjects

Meta-regression

R2 Analog (proportion of variance explained) (%)

IHD

HC

Slope

95% CI

P value

Sample size

8

658

323

0.0099

 − 0.0081; 0.0278

0.2818

26.89

Age (mean, years)

8

658

323

0.1556

0.0339; 0.2772

0.0122

49.96

NOS score

8

658

323

 − 0.9676

 − 2.4017; 0.4665

0.1860

18.80

Sex (male, %)

7

625

285

0.0836

 − 0.1464; 0.3135

0.4762

16.53

  1. P value < 0.05 is shown in Bold