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Table 2 Bivariate meta-regression analysis to analyze the influence of source of heterogeneity on the diagnosis of GCA

From: Accuracy of Doppler ultrasound in the diagnosis of giant cell arteritis: a systematic review and meta-analysis

Variables

Sensitivity (95% CI)

Specificity (95% CI)

Meta-regression (p value)

Probe frequency

≥ 15 MHz

0.84 (0.75–0.89)

0.93 (0.85–0.97)

0.88

< 15 MHz

0.82 (0.69–0.90)

0.92 (0.86–0.95)

Study design

Prospective

0.72 (0.61–0.81)

0.99 (0.82–0.92)

0.44

Retrospective

0.78 (0.69–0.85)

0.93 (0.90–0.97)

Risk of bias

Low

0.82 (0.77–0.86)

0.93 (0.88–0.96)

0.046

Moderate-high

0.71 (0.57–0.82)

0.88 (0.83–0.93)

  1. 95% CI 95% confidence interval