The impact of normal serum complement levels on the disease classification and clinical characteristics in systemic lupus erythematosus

Table 4 Scores in the EULAR/ACR classification criteria between SLE patients with normal and low serum complement levels

	N-com	H-com	p value
	(n = 21)	(n = 96)	p value
Total score of the EULAR/ACR classification criteria, mean
Including complement	19.1 ± 5.9	24.8 ± 6.9	< 0.001
Excluding complement		20.9 ± 6.9	0.266
Score of each domain in the EULAR/ACR classification criteria, mean
Constitutional (Fever)	1.0 ± 1.0	0.46 ± 0.84	0.007
Hematologic	2.0 ± 1.8	2.5 ± 1.6	0.190
Neuropsychiatric	0	0.5 ± 1.3	0.064
Mucocutaneous	4.6 ± 2.6	3.6 ± 2.8	0.236
Serosal	0.7 ± 1.8	1.1 ± 2.1	0.423
Musculoskeletal	4.3 ± 2.8	3.3 ± 3.0	0.150
Renal	0.5 ± 2.1	3.0 ± 4.1	0.003
Antiphospholipid antibody	0.7 ± 0.9	0.8 ± 0.9	0.598
Complement	0	4.0 ± 0.2*	< 0.001
SLE specific antibodies	5.4 ± 1.8	5.7 ± 1.3	0.457

N-com Normal serum levels of C3, C4, and CH50; H-com Less than normal serum levels of one or more complements in C3, C4, and/or CH50; EULAR European League Against Rheumatism; SLE Systemic lupus erythematosus
*The total sample number was 95 because of missing values

ISSN: 2523-3106