The impact of normal serum complement levels on the disease classification and clinical characteristics in systemic lupus erythematosus

Table 1 Classification criteria and disease activity between SLE patients with normal and low serum complement levels

	N-com	H-com	p value
	(n = 21)	(n = 96)	p value
Age, year	31.6 ± 14.1	37.2 ± 16.1	0.126
Female (%)	18 (85.7)	83 (86.5)	0.999
Fulfilled SLE classification criteria (%)
ACR 1997	20 (95.2)	88 (91.7)	1.000
SLICC 2012	20 (95.2)	96 (100)	0.180
EULAR/ACR 2019	20 (95.2)	93 (96.9)	0.552
All three criteria	18 (85.7)	85 (88.5)	0.715
SLEDAI-2 K
Including complement	10.8 ± 5.5	18.4 ± 8.1	< 0.001
Excluding complement	10.8 ± 5.5	16.4 ± 8.1	0.002

SLE Systemic lupus erythematosus; N-com Normal serum levels of C3, C4, and CH50; H-com Less than normal serum levels of one or more complements in C3, C4, and/or CH50; ACR American College of Rheumatology; SLICC Systemic Lupus International Collaborating Clinics; EULAR, European League Against Rheumatism; SLEDAI-2 K SLE Disease Activity Index 2000

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