Fig. 3

Alteration of serum complement levels in the development of relapse or organ damage. Cumulative hypocomplementemia ratio in patients with normal serum levels of C3, C4, and CH50 (N-com) (a). Survival curves in patients with N-com determined by the Kaplan–Meier and log-rank tests showing cumulative hypocomplementemia ratio between those with relapse (black line) and those without relapse (gray line) (b), and between those with organ damage (black line) and those without organ damage (gray line) (c). Cumulative normal complement levels ratio in patients with lower than normal serum levels of one or more complements in C3, C4, and/or CH50 (H-com) (d). Survival curves in patients with H-com determined by the Kaplan–Meier and log-rank tests showing cumulative normal complement levels ratio between those with relapse (black line) and those without relapse (gray line) (e), and between those with organ damage (black line) and those without organ damage (gray line) (f)