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Fig. 5 | Advances in Rheumatology

Fig. 5

From: CD19+CD24highCD27+ B cell and interleukin 35 as potential biomarkers of disease activity in systemic lupus erythematosus patients

Fig. 5

Association of serum IL-35 levels with SLE-related parameters. A Serum IL-35 levels from healthy controls (n = 16), inactive SLE patients (SLEDAI score ≤ 4, n = 10) and active SLE patients (SLEDAI score > 4, n = 14). B Correlation of serum IL-35 levels with the SLEDAI score. C Serum IL-35 levels from anti-dsDNA positive patients (n = 7) and anti-dsDNA negative patients (n = 17). D–F Serum IL-35 levels in SLE patients with rash (n = 11) and without rash (n = 13); with nephritis (n = 14) and without nephritis (n = 10); with hematological disorders (n = 11) and without hematological disorders (n = 13). G–I Correlation of serum IL-35 levels with level of complement C3, C4 and ESR. *P < 0.05, **P < 0.01, ***P < 0.001; ns, not significant

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