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Table 1 Socio-demographic, clinical and therapeutic characteristics of BiobadaBrasil patients included in the present study (n = 105). Values are numbers (%), unless stated otherwise

From: Treatment with biological therapy is associated with faster recovery and lower frequency of treatment switch among rheumatic patients with Chikungunya fever

 

Negative serology n = 55

Positive serology (IgG) n = 50

All patients (n = 105)

  

Asymptomatic (n = 18)

Symptomatic (n = 32)

 

Female

41 (74.5)

12 (66.7)

25 (78.1)

78 (74.3)

Age – years; mean (SD)

50.3 (13.3)

46.3 (15.2)

52.2 (12.7)

50.2 (13.7)

Non-Caucasian

40 (72.7)

13 (72.2)

24 (75.0)

77 (73.3)

Rheumatic disease

RA

AS

PsA

43 (78.2)

8 (14.5)

4 (7.3)

13 (72.2)

5 (27.8)

0 (0.0)

28 (87.5)

4 (12.5)

0 (0.0)

84 (80.0)

17 (16.2)

4 (3.8)

Disease duration – years; median (IQR)

9.0 (4.0–15.0)

7.0 (3.8–11.8)

13.0 (5.2 to 17.8)

9.0 (4.5–15.0)

csDMARD use

Methotrexate

Leflunomide

Antimalarials

Sulfasalazine

21 (38.2)

14 (25.5)

3 (5.5)

4 (7.3)

12 (66.7)

4 (22.2)

0 (0.0)

1 (5.6)

17 (53.1)

9 (28.1)

4 (12.5)

1 (3.1)

50 (47.6)

27 (25.7)

7 (6.7)

6 (5.7)

bDMARD use

Anti-TNF

Abatacept

Rituximab

Tocilizumab

25 (45.5)

3 (5.5)

5 (9.1)

2 (3.6)

8 (44.4)

0 (0.0)

1 (5.6)

0 (0.0)

11 (34.4)

1 (3.1)

1 (3.1)

1 (3.1)

44 (41.9)

4 (3.8)

7 (6.7)

3 (2.9)

IgM for CHIKV

Positive

Borderline

Negative

Not tested

0 (0.0)

1 (1.8)

54 (98.2)

0 (0.0)

8 (44.4)

1 (5.6)

9 (50.0)

0 (0.0)

9 (28.1)

8 (25.0)

13 (40.6)

2 (6.2)

17 (16.2)

10 (9.5)

76 (72.4)

2 (2.0)

  1. SD Standard deviation, RA Rheumatoid arthritis, AS Ankylosing spondylitis, PsA Psoriatic arthritis, IQR Interquartile range, csDMARD Conventional synthetic disease-modifying antirheumatic drugs, Bdmard Biological disease-modifying antirheumatic drugs, TNF Tumor necrosis factor, CHIKV Chikungunya virus