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Table 1 General conditions and serum biomarkers levels in the three groups

From: Serum MMP-9, SP-D, and VEGF levels reflect the severity of connective tissue disease-associated interstitial lung diseases

Group

CTD-ILD (n = 33)

CTD-NILD (n = 31)

HC (n = 24)

Male

9

8

6

Female

24

23

18

Age (years)

61.85 ± 10.35

59.32 ± 12.85

55.83 ± 12.70

Duration (years)

5.54 ± 2.19

6.28 ± 2.41

Smokers

8

7

5

MMP-9 (ng/ml)

466.63 ± 191.09

287.35 ± 110.55*

153.92(115.21–196.88)*&

SP-D(ng/ml)

90.44 ± 22.20

75.19 ± 17.15*

45.14 ± 13.03*&

VEGF (pg/ml)

445.86 ± 145.71

229.35(184.10–306.30) *

206.80 (159.83–226.95)*&

  1. The CTD-NILD group and HC group were compared with the CTD-ILD group
  2. *(P < 0.05); HC group was compared with the CTD-NILD group, &(P < 0.05)