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Table 2 Frequency of early RA treatment in Brazil according to the year of disease onset

From: Decreasing delays in the diagnosis and treatment of rheumatoid arthritis in Brazil: a nationwide multicenter observational study

Disease onset (year)

Delay from symptoms onset to the first DMARD[a],[b]

N*

 ≤ 3 months

 ≤ 6 months

 ≤ 12 months

 ≤ 1990

8.5%

14.9%

33.3%

141

1991–1995

5.3%

15.8%

34.7%

95

1996–2000

12.3%

24.7%

44.5%

146

2001–2005

11.5%

26.3%

49.8%

217

2006–2010

17.2%

38.9%

61.1%

239

2011–2015

17.2%

36.3%

72.0%

157

  1. RA, rheumatoid arthritis; DMARD, disease-modifying anti-rheumatic drug
  2. *Numbers of participants with data available for the analyses
  3. [a]The table shows the frequencies (%) of early RA treatment (early initiation of the first DMARD) considering different delay thresholds (windows of opportunity)
  4. [b]A significant association (p < 0,001) was found between the year of disease onset and the frequency of early RA treatment within all considered windows (delay thresholds); the Mantel–Haenszel linear-by-linear chi-squared test